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CYCS / Cytochrome c
cytochrome c, somatic
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
| Gene Name: | cytochrome c, somatic |
| Synonyms: | CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic |
| Target Sequences: | NM_018947 NP_061820.1 P99999 |
Publications (3)
1
Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease. She P, Zhang Z, Marchionini D, Diaz WC, Jetton TJ, Kimball SR, Vary TC, Lang CH, Lynch CJ. American journal of physiology. Endocrinology and metabolism. 2011 301:E49-61.
[PubMed:21505144]
[PMC:PMC3129844]
Related Antibodies: LS-C41042.
2
Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species. McGuire KA, Barlan AU, Griffin TM, Wiethoff CM. Journal of virology. 2011 85:10806-13.
[PubMed:21835790]
[PMC:PMC3187480]
Related Antibodies: LS-C41042.
3
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Emilie Barruet , Steven M Garcia , Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz. eLife. 2020 Apr;9:e51576. [Full Text Article]
[PubMed:32234209]
[PMC:PMC7164960]
☰ Filters
Products
Antibodies
(147)
ELISA Kits
(34)
Proteins
(13)
Type
Cell-Based
(1)
Custom
(3)
Development Kit
(4)
Over-Expression Lysate
(3)
Primary
(147)
Recombinant
(10)
Sandwich
(23)
Sandwich CLIA
(3)
Target
CYCS / Cytochrome c
(194)
Reactivity
Human
(136)
Mouse
(103)
Rat
(114)
Bovine
(10)
Chicken
(5)
Chimpanzee
(3)
Dog
(18)
Drosophila
(18)
E. coli
(6)
Frog
(8)
Gibbon
(3)
Guinea pig
(2)
Hamster
(7)
Horse
(33)
Monkey
(6)
Orangutan
(3)
Pig
(14)
Pigeon
(4)
Porcine
(1)
Rabbit
(21)
Sheep
(6)
Xenopus
(3)
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IHC
(56)
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(5)
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(30)
WB
(120)
Flo
(31)
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(41)
ICC
(7)
ID
(3)
IE
(3)
IF
(35)
IP
(19)
Neut
(1)
Peptide-ELISA
(3)
Host
rabbit
(72)
mouse
(71)
sheep
(4)
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DevKit DuoPlus
(4)
IHCPlus
(5)
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IgG
(43)
IgG1
(16)
IgG1,k
(5)
IgG1b,k
(7)
IgG2a
(2)
IgG2a,k
(11)
IgG2b
(3)
IgG2b,k
(21)
Clonality
monoclonal mc
(71)
polyclonal pc
(76)
Clone
15F10
(1)
2G8
(1)
4B10
(1)
6H2
(1)
6H2.B4
(5)
7H8.2C12
(10)
7H8.2C12 + CYCS/1010
(3)
8G3
(1)
ABM30D4
(1)
CTC03
(3)
CTC05
(3)
CYCS/1010
(3)
OTI2F2
(2)
SPM389
(2)
Format
12 x 8-Well Microstrips
(3)
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(4)
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(23)
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(4)
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(4)
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(3)
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(6)
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(8)
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(14)
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(6)
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(1)
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(3)
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(3)
DY488 Conjugated
(1)
DY550 Conjugated
(1)
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(9)
HRP Conjugated
(9)
Magnetic beads Conjugated
(1)
PE Conjugated
(7)
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(1)
Ready-to-Use
(4)
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(1)
Unconjugated
(88)
Epitope
aa13-99
(9)
aa1-80
(8)
aa5-100
(8)
aa10-59
(5)
aa91-105
(4)
aa2-105
(2)
aa66-104
(2)
C-Terminus
(1)
His19
(1)
N-Terminus
(1)
aa1-188
(1)
aa1-80, aa81-104, aa66-104
(1)
aa21-55
(1)
aa55-105
(1)
Publications
No
(193)
Yes
(1)
Sample Type
Adherent Cell Cultures
(1)
Cell Culture Supernatants
(7)
Cell Lysates
(8)
Plasma
(20)
Serum
(20)
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(12)
Tag
6His, C-terminus
(2)
6His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(2)
Myc-DDK (Flag)
(4)
TRX-6His, N-terminus
(1)
Species
Human
(9)
Mouse
(2)
Source
293T Cells
(1)
E. coli
(7)
HEK 293 Cells
(3)
Wheat Germ Extract
(2)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(2)
CYCS / Cytochrome c Mouse anti-Horse Monoclonal (7H8.2C12) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$485
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CYCS / Cytochrome c Mouse anti-Mouse Monoclonal (6H2.B4) Antibody
Mouse, Rat, Human
Flo, IF, IP, WB
Unconjugated
25 µg/$264; 100 µg/$342
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
E. coli
GST, N-terminus
39.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CYCS / Cytochrome c Mouse anti-Horse Monoclonal (7H8.2C12) Antibody
Horse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CYCS / Cytochrome c Mouse anti-Pigeon Monoclonal (aa1-80) (7H8.2C12) Antibody
Pigeon, Drosophila, Horse, Mouse, Rat, Hamster, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CYCS / Cytochrome c Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$460
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Ready-to-Use) (7H8.2C12 + CYCS/1010) Antibody
Rat, Pig, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$560
CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, IF, IHC, WB
Unconjugated
1 mg/$513
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$808
CYCS / Cytochrome c Rabbit anti-Horse Polyclonal Antibody
Horse
ELISA, ID, IE, WB
Unconjugated
5 mg/$579
CYCS / Cytochrome c Mouse anti-Horse Monoclonal (CTC03) Antibody
Dog, Bovine, Horse, Human
ELISA, Flo, IP
Unconjugated
100 µl/$333; 500 µl/$587; 1 ml/$742
CYCS / Cytochrome c Sheep anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human
IF, IP, WB
Unconjugated
100 µg/$834
CYCS / Cytochrome c Mouse anti-Human Monoclonal (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$364; 100 µg/$560
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CYCS/1010) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$560
CYCS / Cytochrome c Mouse anti-Human Monoclonal (15F10) Antibody
Mouse, Rat, Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$470
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$364; 100 µg/$560
CYCS / Cytochrome c Mouse anti-Pig Monoclonal (aa1-80) (Azide-free, BSA-free) (7H8.2C12) Antibody
Drosophila, Pig, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$560
CYCS / Cytochrome c Rabbit anti-Human Polyclonal (aa2-105) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$470
CYCS / Cytochrome c Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$567
CYCS / Cytochrome c Mouse anti-Human Monoclonal (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$364; 100 µg/$560
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$560
CYCS / Cytochrome c Mouse anti-Human Monoclonal (Ready-to-Use) (CTC05) Antibody
Drosophila, Horse, Mouse, Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$560
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of 194
product results
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