CXCR4

chemokine (C-X-C motif) receptor 4

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

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Products

ELISA Kits (15)

Type

Cell-Based Phosphorylation (1)

Custom (2)

Sandwich (12)

Target

CXCR4 (15)

Reactivity

Human (6)

Mouse (3)

Rat (4)

Dog (1)

Pig (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (14)

Publications

No (15)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (1)

Cell Lysates (2)

Plasma (9)

Serum (9)

Tissue Homogenates (7)

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Human CXCR4 (Sandwich ELISA) ELISA Kit - LS-F38136

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Human CXCR4 (Sandwich ELISA) ELISA Kit - LS-F11258

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat CXCR4 (Sandwich ELISA) ELISA Kit - LS-F19417

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Bovine CXCR4 (Sandwich ELISA) ELISA Kit - LS-F19415

Type:

Sandwich

Format:

96-Well Strip Plate

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Pig CXCR4 (Sandwich ELISA) ELISA Kit - LS-F11259

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human CXCR4 (Sandwich ELISA) ELISA Kit - LS-F7261

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Mouse CXCR4 (Custom ELISA) ELISA Kit - LS-F19414

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Dog CXCR4 (Custom ELISA) ELISA Kit - LS-F19416

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human CXCR4 (Sandwich ELISA) ELISA Kit - LS-F32744

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat CXCR4 (Sandwich ELISA) ELISA Kit - LS-F32200

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CXCR4 (Sandwich ELISA) ELISA Kit - LS-F51039

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

Select

Human CXCR4 (Sandwich ELISA) ELISA Kit - LS-F50921

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

Select

Mouse CXCR4 (Sandwich ELISA) ELISA Kit - LS-F6189

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$782

Select

Pig CXCR4 (Sandwich ELISA) ELISA Kit - LS-F6720

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$889

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Mouse/Human/Rat Phospho-CXCR4 (Ser339) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1342

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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