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CSF2 / GM-CSF

colony stimulating factor 2 (granulocyte-macrophage)

CSF2 / GM-CSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.

Gene Name: colony stimulating factor 2 (granulocyte-macrophage)
Synonyms: CSF2, Colony-stimulating factor, CSF, GM-CSF, Molgramostin, GMCSF
Target Sequences: NM_000758 NP_000749.2 P04141

Publications (2)

1
Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer. Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S. Cancer research. 2015 75:2629-40. (IHC; Human) [Full Text Article] [PubMed:25952647] Related Antibodies: LS-C104671.
2
Expression of granulocyte macrophage-colony stimulating factor and its receptor in the synovium of osteoarthritis patients is negatively correlated with pain. Eefje M van Helvoort, Niels Eijkelkamp, Floris P J G Lafeber, Simon C Mastbergen. Rheumatology (Oxford, England). 2020 November;59:3452-3457. [Full Text Article] [PubMed:32365364] Related Antibodies: LS-C41956.

☰ Filters
Products
Proteins (59)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Recombinant (55)
CSF2 / GM-CSF (59)
Animal-free (3)
No (59)
6His, C-terminus (8)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His, N-terminus (1)
His,C-terminus (1)
His-GST (2)
His-GST, N-terminus (2)
Myc-DDK (Flag) (3)
Bovine (1)
Human (32)
Monkey-Rhesus (1)
Mouse (14)
Pig (1)
Rat (7)
Rhesus monkey (1)
293F Cells (1)
293T Cells (1)
CHO Cells (3)
E. coli (32)
HEK 293 Cells (5)
Human (1)
Human Cells (3)
Human Embryonic Kidney 293 Cells (1)
Mammalian Cells (5)
Pichia pastoris (1)
Wheat Germ Extract (1)
Yeast (3)
Purified (23)
Low endotoxin level (37)
Biologically active (27)
Animal-free (3)
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
15~19 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$296; 1 mg/$2,653
Select
HEK 293 Cells
His
16.1 kDa
10 µg/$352; 50 µg/$702; 100 µg/$1,042
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
14.5 kDa
5 µg/$268; 20 µg/$349
CSF2 / GM-CSF Protein - Recombinant Colony Stimulating Factor 2, Granulocyte Macrophage By SDS-PAGE
Select
E. coli
His-GST
46.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Select
E. coli
None
14.5 kDa
5 µg/$329; 20 µg/$412; 1000 µg/$3,567
CSF2 / GM-CSF Protein - Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF) by WB
Select
E. coli
His-GST, N-terminus
44kDa
10 µg/$319; 50 µg/$682; 200 µg/$1,270; 100 µg/$1,071; 1 mg/$2,526; 500 µg/$2,025; 5 mg/$4,761; 2 mg/$2,718
Select
HEK 293 Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.5 kDa
20 µg/$379
Select
E. coli
None
Biologically active
Less than 0.3 EU/µg protein (determined by LAL method).
14 kDa
1 mg/$2,653
Select
Pichia pastoris
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.4 kDa
10 µg/$288; 50 µg/$436
Select
Human Embryonic Kidney 293 Cells
His, N-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
16.9 kDa
100 µg/$987; 1 mg/$5,732
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
14.4 kDa
10 µg/$364; 1 mg/$3,661
CSF2 / GM-CSF Protein
Select
E. coli
GST
41.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CSF2 / GM-CSF Protein - Recombinant Colony Stimulating Factor 2, Granulocyte Macrophage By SDS-PAGE
Select
E. coli
His-GST
44.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
22-28 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$296; 1 mg/$2,653
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16-26 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,933
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
14.3 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$1,933
CSF2 / GM-CSF Protein - 12.5% SDS-PAGE of human CSF2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
42.7 kDa
10 µg/$479; 25 µg/$670
Select
None
Biologically active
14.6 kD
20 µg/$476
CSF2 / GM-CSF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.29 kDa
20 µg/$150
Select
Yeast
6His, N-terminus
1 mg/$1,973; 100 µg/$570; 20 µg/$395
CSF2 / GM-CSF Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CSF2 / GM-CSF Protein - Active Colony Stimulating Factor 2, Granulocyte Macrophage By SDS-PAGE
Select
Human
None
50 µg/$542; 10 µg/$297; 200 µg/$1,065; 100 µg/$865; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
CSF2 / GM-CSF Protein - Purified recombinant protein CSF2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
14.4 kDa
20 µg/$1,107
Viewing 1-25 of 59 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).