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CORNIFIN / SPRR1B

small proline-rich protein 1B

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

Gene Name:	small proline-rich protein 1B
Synonyms:	SPRR1B, 14.9 kd pancornulin, 14.9 kDa pancornulin, CORNIFIN, GADD33, SPR-IB, Small proline-rich protein IB, SPRR1, Cornifin B, Cornifin-B, Small proline-rich protein 1B
Target Sequences:	NM_003125 NP_003116.2 P22528

Publications (1)

Meibomian Gland Absence Related Dry Eye in Ectodysplasin A Mutant Mice. Wang YC, Li S, Chen X, Ma B, He H, Liu T, Yu J, Zhang L, Chen Y, Liu Z, Li W. The American journal of pathology. 2016 January;186:32-42. (Human) [Full Text Article] [PubMed:26626448] Related Antibodies: LS-C146187.

CORNIFIN / SPRR1B Protein - 12.5% SDS-PAGE of human SPRR1B stained with Coomassie Blue

Human CORNIFIN / SPRR1B Protein (Recombinant GST) (Full Length) - LS-G30521

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

35.53 kDa

Price:

10 µg/$479; 25 µg/$670

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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