COMP / THBS5

cartilage oligomeric matrix protein

May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

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Products

Antibodies (90)

Type

Primary (90)

Target

COMP / THBS5 (90)

Reactivity

Human (46)

Mouse (44)

Rat (38)

Dog (3)

Horse (3)

Pig (11)

Application

IHC (14)

IHC-Fr (2)

IHC-P (5)

WB (81)

Flo (1)

ELISA (24)

IF (1)

IP (2)

Peptide-ELISA (2)

Host

rabbit (79)

mouse (8)

chicken (2)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG1 (8)

IgG2a (1)

IgY (2)

Clonality

monoclonal mc (9)

polyclonal pc (81)

Clone

12C4 (1)

4H6G10D2 (1)

MA37C94 (HC484D1) (1)

Format

APC (6)

APC Conjugated (7)

Azide-free (1)

Biotin Conjugated (9)

Cy3 Conjugated (6)

Cy7 Conjugated (6)

FITC Conjugated (9)

HRP Conjugated (8)

PE Conjugated (7)

Preservative Free (2)

Unconjugated (38)

more less

Epitope

aa317-455 (10)

aa554-753 (9)

aa123-240 (8)

aa235-423 (8)

aa35-179 (8)

aa40-180 (8)

aa314-343 (7)

N-Terminus (4)

aa20-160 (2)

C-Terminus (1)

Publications

No (89)

Yes (1)

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IHC-plus™ COMP / THBS5 Antibody (clone 12C4) LS-B12308

(5.0) Rating

(1) Publication(s)

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal (12C4) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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COMP / THBS5 Antibody (aa314-343) LS-C166937

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa314-343) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

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COMP / THBS5 Antibody LS-C122806

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$657

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COMP / THBS5 Antibody (aa20-160) LS-C375502

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa20-160) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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COMP / THBS5 Antibody (aa20-160) LS-C375498

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa20-160) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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COMP / THBS5 Antibody (N-Terminus) LS-C345420

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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COMP / THBS5 Antibody (N-Terminus, HRP) LS-C442560

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Horse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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COMP / THBS5 Antibody (N-Terminus, Biotin) LS-C442390

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Horse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

COMP / THBS5 Antibody (aa314-343, Biotin) LS-C276410

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa314-343) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

COMP / THBS5 Antibody LS-C122808

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$657

Select

COMP / THBS5 Antibody LS-C401541

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

COMP / THBS5 Antibody LS-C122807

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$657

Select

COMP / THBS5 Antibody LS-C404832

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

COMP / THBS5 Antibody (aa123-240) LS-C372681

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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COMP / THBS5 Antibody (aa123-240, HRP) LS-C709181

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) (HRP) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

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COMP / THBS5 Antibody (aa123-240, Biotin) LS-C685562

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal (aa123-240) (Biotin) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

COMP / THBS5 Antibody LS-C340761

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$386

Select

COMP / THBS5 Antibody LS-C756549

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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COMP / THBS5 Antibody LS-C782204

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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COMP / THBS5 Antibody (clone MA37C94 (HC484D1)) LS-C745631

Antibody:

COMP / THBS5 Rat anti-Human Monoclonal (MA37C94 (HC484D1)) Antibody

Reactivity:

Human

Applications:

ELISA, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.2 mg/$486

Select

COMP / THBS5 Antibody LS-C153287

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

Select

COMP / THBS5 Antibody LS-C340757

Antibody:

COMP / THBS5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

0.1 mg/$386

Select

COMP / THBS5 Antibody LS-C144592

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

Select

COMP / THBS5 Antibody LS-C834312

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

COMP / THBS5 Antibody LS-C748978

Antibody:

COMP / THBS5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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