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CDH11 / Cadherin 11

cadherin 11, type 2, OB-cadherin (osteoblast)

CDH11 / Cadherin 11 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Gene Name: cadherin 11, type 2, OB-cadherin (osteoblast)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH11, CAD11, Cadherin 11, Cadherin-11, CDHOB, OSF-4, Osteoblast cadherin, OB, OB-cadherin, Ventral neural cadherin, Vnc
Target Sequences: NM_001797 NP_001788.2 P55287

Publications (4)

1
Constitutive Activation of Integrin a9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis. Emori T, Hirose J, Ise K, Yomoda JI, Kasahara M, Shinkuma T, Yoshitomi H, Ito H, Hashimoto M, Sugahara S, Fujita H, Yamamoto N, Morita Y, Narumiya S, Aramori I,. Journal of immunology (Baltimore, Md. : 1950). 2017 199:3427-3436. (WB; Human) [Full Text Article] [PubMed:29038247] Related Antibodies: LS-B2308.
2
Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib. Takashi Emori, Michiko Kasahara, Shingo Sugahara, Motomu Hashimoto, Hiromu Ito, Shuh Narumiya, Yasuyuki Higashi, Yasutomo Fujii. European journal of pharmacology. 2020 September;882:173238. [Full Text Article] [PubMed:32561292] Related Antibodies: LS-B2308.
3
Effects of Qingluo Tongbi Decoction on Gut Flora of Rats with Adjuvant-Induced Arthritis and the Underlying Mechanism. Yan Huang, Meifeng Li, Lingling Zhou, Deguo Xu, Feiya Qian, Junfeng Zhang, Xueping Zhou. Evidence-based complementary and alternative medicine : eCAM. 2019 Aug;2019:6308021. [Full Text Article] [PubMed:31531116] [PMC:PMC6721445] Related Antibodies: LS-C4283.
4
AXL Is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer. Wenting Du, Natalie Z Phinney, Huocong Huang, Zhaoning Wang, Jill Westcott, Jason E Toombs, Yuqing Zhang, Muhammad S Beg, Thomas M Wilkie, James B Lorens, Rolf A Brekken. Molecular cancer research : MCR. 2021 August;19:1412-1421. [Full Text Article] [PubMed:33811159] [PMC:PMC8349827] Related Antibodies: LS-B2308.
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Antibodies (55)
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CDH11 / Cadherin 11 (55)
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CDH11 / Cadherin 11 Antibody - Anti-CDH11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (Intracellular) Antibody
Mouse, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
CDH11 / Cadherin 11 Antibody - Anti-CDH11 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (Intracellular) (5B2H5) Antibody
Mouse, Human
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$485
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (HRP) Antibody
Mouse, Human
ELISA, IHC, IP, WB
HRP Conjugated
100 µl/$1,129
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Human
ELISA, IHC, IP, WB
Biotin Conjugated
100 µl/$1,129
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (FITC) Antibody
Mouse, Human
ELISA, IHC, IP, WB
FITC Conjugated
100 µl/$1,129
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Human
ELISA, IHC, IP, WB
APC Conjugated
100 µl/$1,129
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Human
ELISA, IHC, IP, WB
PE Conjugated
100 µl/$1,129
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (4E12G10) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (2C12A6) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
CDH11 / Cadherin 11 Antibody - Detection limit for recombinant GST tagged CDH11 is approximately 0.3 ng/ml as a capture antibody.
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (4D10) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (Extracellular Domain) (16A) Antibody
Rat, Human
ICC, IHC, IHC-Fr, WB
Unconjugated
100 µg/$740
CDH11 / Cadherin 11 Antibody - Immunofluorescent staining on Cadherin 11 transfected PC3 cells
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (16A) Antibody
Rat, Human
ICC, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$466
CDH11 / Cadherin 11 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 µg/ml
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa637-796) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated
50 µl/$460
CDH11 / Cadherin 11 Antibody - Immunohistochemistry of paraffin-embedded mouse brain using CDH11 antibody at dilution of 1:100 (40x lens).
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CDH11 / Cadherin 11 Antibody - Western blot of OB-cadherin antibody
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (390-470 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa622-650) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa622-650) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
CDH11 / Cadherin 11 Antibody - Western blot of recombinant CDH11 / Cadherin 11.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa374-595) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
CDH11 / Cadherin 11 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CDH11 / Cadherin 11 Antibody - Western blot analysis of lysates from Jurkat cells, using CDH11 Antibody. The lane on the right is blocked with the synthesized peptide.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa421-470) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDH11 / Cadherin 11 Antibody
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CDH11 / Cadherin 11 Mouse anti-Human Monoclonal (16G5) Antibody
Human
ICC, IF, IP, WB
Unconjugated
0.1 mg/$482
CDH11 / Cadherin 11 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer at dilution of 1:100
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CDH11 / Cadherin 11 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal (aa637-796) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CDH11 / Cadherin 11 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CDH11 / Cadherin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).