CD59

CD59 molecule, complement regulatory protein

CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

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Products

Proteins (30)

Type

Over-Expression Lysate (11)

Recombinant (19)

Target

CD59 (30)

Application

SDS-PAGE (1)

Publications

No (30)

Tag

6His, C-terminus (1)

6His, N-terminus (2)

Fc, C-terminus (1)

GST (2)

His (3)

His, N-terminus (1)

His,C-terminus (2)

His-S (5)

His-T7 (1)

Myc-DDK (Flag) (12)

Species

Human (22)

Mouse (3)

Pig (1)

Rabbit (1)

Rat (2)

Rhesus monkey (1)

Source

293T Cells (11)

E. coli (10)

HEK 293 Cells (5)

Human (1)

Human Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (6)

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Human CD59 Protein (Recombinant 6His, N-terminus) (aa26-102) - LS-G22850

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

11 kD

Price:

1 mg/$1,607; 100 µg/$469; 20 µg/$349

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Mouse CD59 Protein (Recombinant His) (Met1-Lys95) - LS-G98727

Source:

HEK 293 Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

9.7 kDa

Price:

50 µg/$721

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Human CD59 Protein (Recombinant His-S) (aa26-102) - LS-G13674

Source:

E. coli

Tag:

His-S

Molecular Weight:

14.7 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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Human CD59 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65211

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$1,107

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Human CD59 Protein (Recombinant 6His, C-terminus) - LS-G146166

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

9.8 kDa

Price:

10 µg/$273; 50 µg/$398

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Human CD59 Protein (Recombinant His, N-terminus) - LS-G146199

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

10.2kDa

Price:

20 µg/$270; 100 µg/$390

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Mouse CD59 Protein (Recombinant Fc, C-terminus) (Met1-Lys95) - LS-G140775

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.4 kDa

Price:

50 µg/$721

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Human CD59 Protein (Recombinant GST) (aa26-102) - LS-G20580

Source:

E. coli

Tag:

GST

Molecular Weight:

36.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CD59 Protein (Recombinant His) - LS-G2491

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human CD59 Protein (Recombinant GST) (Full Length) - LS-G27831

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

40.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CD59 Protein (Recombinant 6His, N-terminus) (Leu26-Asn102) - LS-G26551

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

11.2 kDa

Price:

10 µg/$265; 50 µg/$315; 200 µg/$484

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Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75089

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.18 kDa

Price:

20 µg/$150

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Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75092

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75091

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75090

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.18 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75093

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75094

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.18 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75095

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.18 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75096

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.18 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75097

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75098

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75099

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.6 kDa

Price:

20 µg/$150

Select

Human CD59 Protein (Recombinant His,C-terminus) (Met1-Glu101) - LS-G50844

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human CD59 consists of 87 amino acids and has a predicted molecular mass of 10.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD59 is approximately 13-19 kDa due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human CD59 Protein (Recombinant His,C-terminus) (Met1-Glu101) - LS-G138004

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

10.2 kDa

Price:

100 µg/$721

Select

Rat CD59 Protein (Recombinant His) (Met1-Asn100) - LS-G98340

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

10.3 kDa

Price:

100 µg/$843

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