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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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CD22

CD22 molecule

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Gene Name: CD22 molecule
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: CD22, CD22 molecule, CD22 antigen, SIGLEC2, SIGLEC-2, T-cell surface antigen Leu-14, B-cell receptor CD22, BL-CAM
Target Sequences: NM_001771 NP_001762.2 P20273

Publications (1)

1
Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid -lactamase display. Bannister D, Popovic B, Sridharan S, Giannotta F, File P, Yilmaz N, Minter R. Protein engineering, design & selection : PEDS. 2011 24:351-60. (IP) [PubMed:21159620] [PMC:PMC3049344]

☰ Filters
CD22 (235)
No (235)
Viewing 1-25 of 235 items
CD22 Antibody - Anti-CD22 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Mouse Monoclonal [clone 1B1] (IgG1) to Human CD22
Human
IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
CD22 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal [clone 2B12] (IgG1) to Human CD22
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
CD22 Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-CD22 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI4C3] (IgG1) to Human CD22
Mouse, Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
CD22 Antibody - Flow cytometry of CD22 antibody
Select
Mouse Monoclonal [clone RFB4] (IgG1) to Human CD22
Human
Flo, IHC, IHC-P
Unconjugated
100µg   1mg/ml   $315.00
Select
Mouse Monoclonal [clone IS7] (IgG1) to Human CD22
Human
Flo
APC Conjugated
100tst   $315.00
CD22 Antibody - Surface staining of CD22 in human peripheral blood cells with anti-CD22 (IS7) azide free, GAM-APC.
Select
Mouse Monoclonal [clone IS7] (IgG1) to Human CD22
Human
Flo
Unconjugated, Azide-free
0.1mg   1mg/ml   $255.00
CD22 Antibody - Flow cytometry of CD22 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone RFB4] (IgG1) to Human CD22
Human
Flo, IHC, IHC-P
Unconjugated, Azide-free
100µg   1mg/ml   $315.00
Select
Mouse Monoclonal [clone MEM-01] (IgG1) to Human CD22
Human, Non-Human Primates
Flo, IP, WB
Unconjugated
0.1mg   1mg/ml   $255.00
CD22 Antibody - Surface staining of human peripheral blood cells with anti-CD22 (MEM-01) biotin / streptavidin-APC.
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Mouse Monoclonal [clone MEM-01] (IgG1) to Human CD22
Human, Non-Human Primates
Flo, IP, WB
Biotin Conjugated
0.1mg   1mg/ml   $290.00
Select
Rabbit Polyclonal (IgG) to Human CD22
Human
ELISA, WB
HRP Conjugated
100µl   0.8mg/ml   $545.00
Select
Mouse Monoclonal [clone MYG13] (IgG1) to Human CD22
Mouse, Rat, Human
ELISA, Flo, IF, IHC, IHC-Fr, IP
Unconjugated
100µg   $485.00
CD22 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human CD22
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100µg   1mg/ml   $295.00
CD22 Antibody - Western blot analysis of extracts of various cell lines, using CD22 antibody.
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Rabbit Polyclonal (IgG) to Human CD22
Mouse, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
CD22 Antibody - CD22 antibody. IHC(P): Human Tonsil Tissue.
Select
Rabbit Polyclonal to Human CD22
Human
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $355.00
CD22 Antibody - Human peripheral blood lymphocytes stained with purified HIB22, followed by anti-mouse IgGs FITC
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Mouse Monoclonal [clone HIB22] (IgG1) to Human CD22
Human
Flo, IHC, IHC-Fr
Unconjugated
100µg   0.5mg/ml   $225.00
CD22 Antibody - CD22 antibody IHC-paraffin. IHC(P): Human Tonsil Tissue.
Select
Rabbit Polyclonal to Human CD22
Human
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
Select
Mouse Monoclonal [clone MEM-01] (IgG1) to Human CD22
Human
Flo, IP, WB
Unconjugated
0.2mg   1mg/ml   $405.00
CD22 Antibody - IHC of paraffin-embedded Human tonsil using anti-CD22 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)(1:150).
Select
Mouse Monoclonal [clone OTI2E6] (IgG2b) to Human CD22
Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
Select
Rabbit Polyclonal to Human CD22
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
30µg   $245.00; 100µg   500µl   $385.00
Select
Rat Monoclonal [clone 2D6] (IgG1) to Mouse CD22
Mouse
Flo, IP
Unconjugated
500µg   $495.00
Select
Rat Monoclonal [clone 2D6] (IgG1) to Mouse CD22
Flo, IP
Unconjugated
2.5ml   2mg/ml   $4,455.00
CD22 Antibody - IHC of paraffin-embedded cervical cancer tissues using ZEB1 mouse monoclonal antibody with DAB staining.
Select
Mouse Monoclonal [clone 2H1C4] (IgG1) to Human CD22
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µg   $365.00
CD22 Antibody - Immunofluorescence of HeLa cells using CD22 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Select
Mouse Monoclonal [clone 1A3A11] (IgG1) to Human CD22
Human
ELISA, Flo, IF, WB
Unconjugated
100µg   $365.00
Select
Rat Monoclonal [clone OX-96] (IgG1) to Mouse CD22
Mouse
Flo
FITC Conjugated
0.1mg   $355.00
CD22 Antibody - IHC testing of FFPE human tonsil tissue with CD22 antibody (clone BLCAM/1795). Required HIER: boil tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
Select
Mouse Monoclonal [clone BLCAM/1795] (IgG1,k) to Human CD22
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $255.00; 100µg   0.2mg/ml   $395.00

Viewing 1-25 of 235 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).