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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BRAP2

BRCA1 associated protein

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Gene Name: BRCA1 associated protein
Synonyms: BRAP, BRAP2, IMP, Galectin-2-binding protein, RING finger protein 52, RNF52, BRCA1 associated protein, BRCA1-associated protein
Target Sequences: NM_006768 NP_006759.3 Q7Z569

Filtered by: None
Target
BRAP2 (26)
Reactivity
Human (26)
Mouse (4)
Bat (4)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (4)
Hamster (4)
Horse (4)
Monkey (5)
Application
IHC (2)
IHC-P (4)
WB (17)
Flo (4)
ELISA (12)
IF (6)
IP (2)
Host
rabbit (20)
mouse (6)
Isotype
IgG (15)
IgG1 (4)
Clonality
monoclonal mc (6)
polyclonal pc (20)
Clone
BRCA1/1398 (2)
BRCA1/1472 (2)
Format
AP Conjugated (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa66-95 (8)
C-Terminus (4)
aa510-560 (1)
aa560-592 (1)
aa67-79 (1)
Publications
No (26)
Showing 1-25 of 26 results

IHC-plus™ BRAP2 Antibody (aa67-79) LS-B3402
Rabbit Polyclonal to Human BRAP2
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-BRAP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

BRAP2 Antibody LS-C671666
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

BRAP2 Antibody (HRP) LS-C671665
Rabbit Polyclonal (IgG) to Human BRAP2
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

BRAP2 Antibody (Biotin) LS-C671668
Rabbit Polyclonal (IgG) to Human BRAP2
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

BRAP2 Antibody (clone BRCA1/1472) LS-C761404
Mouse Monoclonal [clone BRCA1/1472] (IgG1) to Human BRAP2
Human
ELISA, Flo, IF
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00

BRAP2 Antibody (clone BRCA1/1472) LS-C761406
Mouse Monoclonal [clone BRCA1/1472] (IgG1) to Human BRAP2
Human
ELISA, Flo, IF
Unconjugated
100µg 1mg/ml  $465.00

BRAP2 Antibody (clone BRCA1/1398) LS-C761407
Mouse Monoclonal [clone BRCA1/1398] (IgG1) to Human BRAP2
Human
Flo, IF, IHC-P
Unconjugated
100µg 1mg/ml  $465.00
IHC testing of FFPE human breast carcinoma tissue with BRCA1 antibody (clone BRCA1/1398). HIER: boil tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min.

BRAP2 Antibody (clone BRCA1/1398) LS-C761409
Mouse Monoclonal [clone BRCA1/1398] (IgG1) to Human BRAP2
Human
Flo, IF, IHC-P
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
IHC testing of FFPE human breast carcinoma tissue with BRCA1 antibody (clone BRCA1/1398). HIER: boil tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min.

BRAP2 Antibody LS-C807817
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

BRAP2 Antibody (aa66-95) LS-C319868
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
Unconjugated
200µl  $590.00

BRAP2 Antibody (aa66-95, Biotin) LS-C252664
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

BRAP2 Antibody (aa66-95, FITC) LS-C252665
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

BRAP2 Antibody (aa66-95, AP) LS-C252662
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
AP Conjugated
200µl  $740.00

BRAP2 Antibody (aa66-95, Azide-free, HRP) LS-C252666
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

BRAP2 Antibody (aa66-95, PE) LS-C252667
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
PE Conjugated
200µl  $740.00

BRAP2 Antibody (aa66-95, APC) LS-C252663
Rabbit Polyclonal (IgG) to Human BRAP2
Human
ELISA, WB
APC Conjugated
200µl  $740.00

BRAP2 Antibody (aa560-592) LS-C289402
Rabbit Polyclonal (IgG) to Human BRAP2
Human
IP, WB
Unconjugated
100µl 1mg/ml  $395.00

BRAP2 Antibody LS-C393632
Mouse Monoclonal to Human BRAP2
Human
WB
Unconjugated
100µl  $325.00
Western blot analysis of extracts from CHO-K1 cells, transfected with a human pFLAG-CMV2-BRAP construct (A) or transfected with a human pFLAG-CMV2 construct (B), using BRAP mouse monoclonal antibody (1:1000 dilution).

BRAP2 Antibody (aa66-95) LS-C157585
Rabbit Polyclonal to Human BRAP2
Human
WB
Unconjugated
400µl  $325.00
BRAP Antibody western blot of 293 cell line lysates (35 ug/lane). The BRAP antibody detected the BRAP protein (arrow).

BRAP2 Antibody (C-Terminus) LS-C110753
Rabbit Polyclonal to Human BRAP2
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BRAP2 Antibody (C-Terminus, HRP) LS-C444639
Rabbit Polyclonal to Human BRAP2
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BRAP2 Antibody (C-Terminus, Biotin) LS-C444637
Rabbit Polyclonal to Human BRAP2
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BRAP2 Antibody (C-Terminus, FITC) LS-C444638
Rabbit Polyclonal to Human BRAP2
Chicken, Bovine, Mouse, Dog, Hamster, Horse, Bat, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
BRAP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BRAP2 Antibody (aa510-560) LS-C289403
Rabbit Polyclonal (IgG) to Human BRAP2
Human
IP
Unconjugated
100µl 1mg/ml  $395.00

BRAP2 Antibody (AP) LS-C411418
Mouse Monoclonal (IgG) to Human BRAP2
Human
WB
AP Conjugated
50µl  $285.00; 100µl  $375.00; 200µl  $495.00
Western blot analysis of extracts of various cells.
Showing 1-25 of 26 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).