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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BMP4

bone morphogenetic protein 4

BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene Name: bone morphogenetic protein 4
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP4, BMP-2B, BMP-4, BMP2B, BMP2B1, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, DVR4, MCOPS6, OFC11, Zyme
Target Sequences: NM_001202 NP_001193.2 P12644

Publications (1)

1
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM. Science immunology. 2018 January;3:pii: eaal2736. [Full Text Article] [PubMed:29330161] [PMC:PMC5795617]

Filtered by: None
Target
BMP4 (132)
Reactivity
Human (74)
Mouse (29)
Rat (41)
Bat (9)
Bovine (17)
Chicken (10)
Chimpanzee (3)
Cow (8)
Dog (9)
Gibbon (6)
Goat (9)
Guinea pig (4)
Hamster (1)
Horse (5)
Monkey (5)
Pig (25)
Rabbit (18)
Sheep (8)
Xenopus (1)
Zebrafish (4)
Application
IHC (15)
IHC-P (5)
WB (123)
Flo (4)
ELISA (23)
ICC (16)
IF (8)
IP (8)
Peptide-ELISA (3)
PMA (2)
Host
rabbit (100)
mouse (23)
goat (1)
guinea pig (8)
Isotype
IgG (19)
IgG1 (8)
IgG2b (11)
IgM,k (1)
Clonality
monoclonal mc (23)
polyclonal pc (109)
Clone
10F4B4 (2)
26H16 (1)
3C11C7 (1)
3C11H8 (1)
3H2 (1)
3H2.3 (1)
OTI1C2 (1)
OTI1D1 (1)
OTI6B7 (2)
UMAB42 (2)
Format
AP Conjugated (1)
APC (9)
APC Conjugated (10)
Biotin Conjugated (13)
Carrier-free (2)
Cy3 Conjugated (9)
Cy7 Conjugated (9)
FITC Conjugated (14)
HRP Conjugated (13)
PE Conjugated (11)
Unconjugated (52)
Epitope
aa293-408 (13)
aa209-392 (8)
aa219-392 (8)
aa22-408 (8)
aa227-408 (8)
aa23-204 (8)
aa244-388 (8)
aa25-201 (8)
aa28-183 (8)
aa23-72 (4)
aa264-313 (4)
aa20-34 (1)
aa253-302 (1)
aa293-324 (1)
internal region (1)
Publications
No (132)
Showing 1-25 of 132 results

IHC-plus™ BMP4 Antibody LS-B2842
Rabbit Polyclonal (IgG) to Human BMP4
Xenopus, Chicken, Bovine, Rabbit, Mouse, Goat, Dog, Bat, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-BMP4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot Image

IHC-plus™ BMP4 Antibody LS-B3101
Rabbit Polyclonal to Human BMP4
Chicken, Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-BMP4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BMP4 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

BMP4 Antibody (clone 3H2.3) LS-C4214
Mouse Monoclonal [clone 3H2.3] (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
Unconjugated
100µg 1mg/ml  $665.00

BMP4 Antibody (HRP) LS-C543768
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
HRP Conjugated
100µl  $845.00

BMP4 Antibody (Biotin) LS-C523641
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
Biotin Conjugated
100µl  $845.00

BMP4 Antibody (FITC) LS-C533670
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
FITC Conjugated
100µl  $845.00

BMP4 Antibody (AP) LS-C505704
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
AP Conjugated
100µl  $845.00

BMP4 Antibody (PE) LS-C651870
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
PE Conjugated
100µl  $845.00

BMP4 Antibody (APC) LS-C515318
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
APC Conjugated
100µl  $845.00

IHC-plus™ BMP4 Antibody (aa20-34) LS-B787
Rabbit Polyclonal to Human BMP4
Human
ELISA, IHC, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-BMP4 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

BMP4 Antibody LS-C104439
Mouse Monoclonal (IgG2b) to Human BMP4
Human
ELISA, WB
Unconjugated
500µg  $255.00

BMP4 Antibody LS-C403867
Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human brain using BMP4 Polyclonal Antibody at dilution of 1:25.
Western blot analysis of Mouse intestinumm tenue tissue, using BMP4 Polyclonal Antibody at dilution of 1:450.

BMP4 Antibody LS-C331543
Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat
IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human prostate cancer tissue.
Immunohistochemistry of paraffin-embedded mouse lung tissue.

BMP4 Antibody (aa293-408, clone UMAB42) LS-C796714
Mouse Monoclonal [clone UMAB42] (IgG1) to Human BMP4
Human
IF, IHC, PMA, WB
Unconjugated
100µl  $395.00
Immunohistochemical staining of paraffin-embedded human stomach carcinoma using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.
Immunohistochemical staining of paraffin-embedded human small intestine using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.

BMP4 Antibody (clone 3H2, FITC) LS-C183372
Mouse Monoclonal [clone 3H2] (IgG2b) to Mouse BMP4
Mouse, Human
Flo
FITC Conjugated
100tst  $590.00

BMP4 Antibody LS-C318250
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry Image
Immunohistochemistry Image

BMP4 Antibody (HRP) LS-C318252
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, WB
HRP Conjugated
50µg  $285.00; 100µg 0.42mg/ml  $385.00

BMP4 Antibody (aa293-408, clone UMAB42, Carrier-free) LS-C796713
Mouse Monoclonal [clone UMAB42] (IgG1) to Human BMP4
Human
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100µg  $425.00
Immunohistochemical staining of paraffin-embedded human stomach carcinoma using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.
Immunohistochemical staining of paraffin-embedded human small intestine using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.

BMP4 Antibody (aa219-392) LS-C293039
Rabbit Polyclonal to Cow BMP4
Mouse, Bovine, Rat, Cow, Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $560.00
Western blot of recombinant BMP4 / BMP-4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BMP4 Antibody LS-C483081
Mouse Monoclonal to Human BMP4
Human
Flo, ICC, IF
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

BMP4 Antibody (clone 3C11H8) LS-C669375
Mouse Monoclonal [clone 3C11H8] (IgG1) to Human BMP4
Human
ELISA, IF, WB
Unconjugated
0.1mg  $365.00

BMP4 Antibody LS-C659397
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, IHC, WB
Unconjugated
100µg  $405.00

BMP4 Antibody LS-C746936
Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat, Human
IF, IHC
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded human prostate cancer using BMP4 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using BMP4 antibody at dilution of 1:100 (40x lens).

BMP4 Antibody (clone 3C11C7) LS-C669376
Mouse Monoclonal [clone 3C11C7] (IgG1) to Human BMP4
Human
ELISA, Flo
Unconjugated
0.1mg  $365.00

BMP4 Antibody LS-C667714
Rabbit Polyclonal to Human BMP4
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image
Showing 1-25 of 132 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).