Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

We could not find product '(ID:90043)'. Here are some alternate products to this target that might be of interest to you.



APC

Adenomatous Polyposis Coli

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

Gene Name: Adenomatous Polyposis Coli
Synonyms: APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3
Target Sequences: NM_000038 NP_000029.2 P25054

Publications (2)

1
Cadherins, catenins and APC in pleural malignant mesothelioma. Abutaily AS, Collins JE, Roche WR. The Journal of pathology. 2003 201:355-62. [PubMed:14595746]
2
DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition. Ollier M, Radosevic-Robin N, Kwiatkowski F, Ponelle F, Viala S, Privat M, Uhrhammer N, Bernard-Gallon D, Penault-Llorca F, Bignon YJ, Bidet Y. American journal of cancer research. 2015 5:2113-26. (ICC, IHC; Human) [PubMed:26328243] [PMC:PMC4548324]

Viewing 1-25 of 77 items
APC Antibody - Anti-APC antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
APC Antibody - Anti-APC antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
250µl   $485.00
APC Antibody - Western blot of APC antibody
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
APC Antibody - Western blot analysis of APC (pS2054) expression in HeLa (A); Caco2 (B); SW480 (C); MCF7 (D); SP2/0 (E); PC12 (F) whole cell lysates.
Select
Rabbit Polyclonal to Human APC
Mouse, Rat, Pig, Human, Monkey
WB
Unconjugated
100µl   1mg/ml   $265.00
APC Antibody - Immunohistochemical analysis of APC staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human APC
Chicken, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
APC Antibody - Immunohistochemical analysis of APC staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human APC
Mouse, Rat, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
30µl   1mg/ml   $205.00; 100µl   1mg/ml   $245.00; 200µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Human
ELISA, WB
Unconjugated
200µl   $590.00
APC Antibody - Detection of Human APC by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-APC used at a dilution of 1:250.
Select
Rabbit Polyclonal (IgG) to Human APC
Human
IHC
Unconjugated
100µl   $415.00
APC Antibody
Select
Rabbit Polyclonal (IgG) to Human APC
Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
APC Antibody
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
APC Antibody - IHC of APC (Q2829) pAb in paraffin-embedded human lung carcinoma tissue.
Select
Rabbit Polyclonal to Human APC
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
APC Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APC mouse monoclonal antibody. (heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
Mouse Monoclonal [clone OTI2B8] (IgG1) to Human APC
Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
APC Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APC mouse monoclonal antibody. (heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
Mouse Monoclonal [clone OTI2B8] (IgG1) to Human APC
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rat Monoclonal (IgG2a) to Mouse APC
Human
ELISA, IF, WB
Unconjugated
100µg   $415.00
Select
Rat Monoclonal [clone T45] (IgG2a) to Mouse APC
Human
ELISA, IF, WB
Unconjugated
100µg   $415.00
Select
Rat Monoclonal (IgG2a) to Mouse APC
Mouse
ELISA, IF, WB
Unconjugated
100µg   $530.00
APC Antibody - Western blot analysis of extracts of 293T cells, using APC antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Select
Rabbit Polyclonal (IgG) to Human APC
Rat, Human
ICC, IHC, IP, WB
AP Conjugated
50µl   $315.00; 100µl   $425.00; 200µl   $650.00
APC Antibody - Immunofluorescence of monoclonal antibody to APC on HeLa cell . [antibody concentration 10 ug/ml]
Select
Mouse Monoclonal [clone 3E2] (IgG1,k) to Human APC
Human
ELISA, IF, WB
Unconjugated
100µg   $365.00
APC Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using APC (Phospho-Ser2054) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human APC
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human APC
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
APC Antibody - Western blot analysis of extracts from HUVEC cells, treated with PMA (125ng/ml, 30mins), using APC (Phospho-Ser2054) antibody.
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
Select
Mouse Monoclonal (IgG1) to Human APC
Human
IHC, IHC-Fr, WB
Unconjugated
50µg   $455.00
APC Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using APC antibody.
Select
Rabbit Polyclonal (IgG) to Human APC
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   100µl   1µg/µl   $305.00
Select
Goat Polyclonal (IgG) to Human APC
Human
ELISA, IHC, WB
Unconjugated
100µg   $770.00
Select
Rat Monoclonal (IgG2a) to Mouse APC
Mouse
IF, WB
Unconjugated
100µg   $530.00

Viewing 1-25 of 77 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).