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ALOX15B / 15-LOX-2

arachidonate 15-lipoxygenase, type B

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

Gene Name: arachidonate 15-lipoxygenase, type B
Family/Subfamily: Lipoxygenase , Not assigned-Other
Synonyms: ALOX15B, 15S-lipoxygenase, 15-lipoxygenase 2, 15-LOX-2, 15-LOX-B, Arachidonate 15-lipoxygenase B, Arachidonate 15-lipoxygenase 2
Target Sequences: NM_001141 NP_001132.2 O15296

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Products
Antibodies (49)
Primary (49)
ALOX15B / 15-LOX-2 (49)
Human (41)
Mouse (10)
Rat (14)
Bovine (9)
Chimpanzee (9)
Dog (3)
Guinea pig (3)
Horse (6)
Monkey (3)
Pig (9)
Rabbit (6)
IHC (8)
IHC-P (5)
WB (41)
ELISA (12)
ICC (1)
IF (4)
IP (1)
rabbit (48)
mouse (1)
Product Group
IHCPlus (2)
IgG (22)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (48)
4A7 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (2)
Unconjugated (20)
aa253-490 (8)
aa349-633 (8)
N-Terminus (4)
aa1-676 (4)
aa254-303 (4)
aa401-450 (4)
aa585-634 (4)
aa1-200 (2)
aa161-179 (1)
aa21-262 (1)
aa597-627 (1)
No (49)
ALOX15B / 15-LOX-2 Antibody - Anti-ALOX15B / 15 Lipoxygenase 2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa161-179) Antibody
Human
IHC, IHC-P, WB
Unconjugated
1 Each/$485
ALOX15B / 15-LOX-2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ALOX15B / 15-LOX-2 Antibody - Formalin-fixed and paraffin-embedded human skin tissue reacted with ALOX15B Antibody ,which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa597-627) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALOX15B / 15-LOX-2 Antibody - Western blot of recombinant ALOX15B / 15 Lipoxygenase 2.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa253-490) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
ALOX15B / 15-LOX-2 Antibody - Western blot of recombinant ALOX15B / 15 Lipoxygenase 2.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa253-490) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511
ALOX15B / 15-LOX-2 Antibody - Western blot of recombinant ALOX15B / 15 Lipoxygenase 2.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa253-490) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
ALOX15B / 15-LOX-2 Antibody - Immunohistochemistry of paraffin-embedded Mouse lung tissue.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ALOX15B / 15-LOX-2 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IP, WB
Unconjugated
100 µl/$709
ALOX15B / 15-LOX-2 Antibody - Immunofluorescence of monoclonal antibody to ALOX15B on HeLa cell . [antibody concentration 10 ug/ml]
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ALOX15B / 15-LOX-2 Mouse anti-Human Monoclonal (4A7) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
ALOX15B / 15-LOX-2 Antibody
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa21-262) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
ALOX15B / 15-LOX-2 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-200) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
ALOX15B / 15-LOX-2 Antibody - ALOX15B / 15 Lipoxygenase 2 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa401-450) Antibody
Human
WB
Unconjugated
100 µl/$424
ALOX15B / 15-LOX-2 Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa585-634) Antibody
Human
WB
Unconjugated
100 µl/$397
ALOX15B / 15-LOX-2 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ALOX15B / 15-LOX-2 Antibody - Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
WB
Unconjugated
100 µl/$424
ALOX15B / 15-LOX-2 Antibody - Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa254-303) (HRP) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ALOX15B / 15-LOX-2 Antibody - Immunofluorescence staining of A549 cells with ALOX15B Antibody at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-676) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-676) (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-676) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ALOX15B / 15-LOX-2 Rabbit anti-Human Polyclonal (aa1-676) (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 49 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).