LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Immunohistochemistry Reagents
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Research Areas
  • Cancer Research:
  • Breast Cancer IHC
  • Colorectal Cancer IHC
  • Lung Cancer IHC
  • Prostate Cancer IHC
  • Cell Cycle:
  • Apoptosis
  • Protein Family and Group:
  • Caspases
  • Chemokines
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Reviews
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Unfortunately, the antibody (ID:156023) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



ADAM17 / TACE

ADAM metallopeptidase domain 17

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease.

Gene Name: ADAM metallopeptidase domain 17
Family/Subfamily: Protease , Metallopeptidase M12B
Synonyms: ADAM17, CD156B, CD156b antigen, CSVP, ADAM 17, NISBD, TNF-alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Snake venom-like protease, TACE
Target Sequences: NM_003183 NP_003174.3 P78536

Publications (1)

1
CD44 Interacts with HIF-2a to Modulate the Hypoxic Phenotype of Perinecrotic and Perivascular Glioma Cells. Johansson E, Grassi ES, Pantazopoulou V, Tong B, Lindgren D, Berg TJ, Pietras EJ, Axelson H, Pietras A. Cell reports. 2017 20:1641-1653. (IF; Mouse) [Full Text Article] [PubMed:28813675] Related Antibodies: LS-B619.

Filtered By: None
Target
adam17-tace (88)
Reactivity
Human (75)
Mouse (17)
Rat (30)
Bat (1)
Bovine (1)
Chicken (1)
Mammal (5)
Monkey (2)
Application
IHC (26)
IHC-P (5)
WB (81)
Flo (9)
ELISA (30)
ICC (5)
IF (2)
IP (3)
Peptide-ELISA (4)
PLA (1)
Host
rabbit (74)
mouse (13)
goat (1)
Isotype
IgG (68)
IgG2b,k (1)
Clonality
monoclonal mc (13)
polyclonal pc (75)
Clone
1F6 (1)
Format
AP Conjugated (3)
APC (3)
APC Conjugated (5)
Azide-free (3)
Biotin Conjugated (10)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (9)
HRP Conjugated (7)
PE Conjugated (6)
Unconjugated (42)
Epitope
aa226-473 (18)
C-Terminus (10)
aa221-451 (10)
aa195-224 (8)
aa794-823 (8)
pThr735 (3)
aa807-823 (2)
Cleaved (1)
Cleaved Arg215 (1)
Internal (1)
aa1-671 (1)
aa196-245 (1)
aa670-750 (1)
aa701-750 (1)
aa806-824 (1)
aa811-824 (1)
Publications
No (87)
Yes (1)
Showing 1-25 out of 88 results
ADAM17 / TACE Antibody (aa807-823) IHC-plus™ LS-B619
Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B619 concentration 20 ug/ml.
Western blot of anti-TACE (CT) antibody at 1 ug/ml on HeLa (1,3) an Jurkat (2,4) whole cell lysate in the absence (1,2) and presence (3,4) of blocking peptide.

Rabbit Polyclonal to Human ADAM17 / TACE
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
ADAM17 / TACE Antibody (clone 1F6) IHC-plus™ LS-B4426
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4426 concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4426 concentration 5 ug/ml.

Mouse Monoclonal [clone 1F6] (IgG2b,k) to Human ADAM17 / TACE
Human
ELISA IHC IHC-P PLA WB
Unconjugated
ADAM17 / TACE Antibody (C-Terminus) IHC-plus™ LS-B1821
Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1821 concentration 20 ug/ml.

Rabbit Polyclonal to Human ADAM17 / TACE
Human
ELISA IHC IHC-P WB
Unconjugated
ADAM17 / TACE Antibody (C-Terminus) LS-C263
Immunocytochemistry of TACE in HeLa cells with TACE antibody at 10 µg/ml.
Immunocytochemistry of TACE in HeLa cells with TACE antibody at 10 µg/mL.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
ICC WB
Unconjugated
ADAM17 / TACE Antibody (aa811-824) IHC-plus™ LS-B4437
Anti-ADAM17 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4437 concentration 3.75 ug/ml.
Anti-ADAM17 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4437 concentration 3.75 ug/ml.

Goat Polyclonal to Human ADAM17 / TACE
Chicken, Bovine, Bat, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
ADAM17 / TACE Antibody (phospho-Thr735) LS-C198591
Western blot of extracts from K562 cells treated with UV 5', using ADAM 17 (Phospho-Thr735) Antibody. The lane on the right was incubated with synthetic peptide.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
ADAM17 / TACE Antibody (phospho-Thr735) LS-C380935

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
ADAM17 / TACE Antibody (C-Terminus) LS-C137039
Western blot Image

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA IHC WB
Unconjugated
ADAM17 / TACE Antibody (aa195-224) LS-C329200

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
Unconjugated
ADAM17 / TACE Antibody (aa195-224, Biotin) LS-C212598

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
Biotin Conjugated
ADAM17 / TACE Antibody (aa195-224, FITC) LS-C212600

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
FITC Conjugated
ADAM17 / TACE Antibody (aa195-224, APC) LS-C212599

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
APC Conjugated
ADAM17 / TACE Antibody (aa195-224, Azide-free, HRP) LS-C212601

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
HRP Conjugated, Azide-free
ADAM17 / TACE Antibody (aa195-224, PE) LS-C212604

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
PE Conjugated
ADAM17 / TACE Antibody (aa195-224, AP) LS-C212597

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
AP Conjugated
ADAM17 / TACE Antibody (aa196-245) LS-C121045
Western blot of extracts from rat liver cells, using ADAM 17 (Cleaved-Arg215) Antibody. The lane on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
Peptide-ELISA WB
Unconjugated
ADAM17 / TACE Antibody (C-Terminus) LS-C18008

Rabbit Polyclonal (IgG) to Rat ADAM17 / TACE
Mouse, Rat
ELISA WB
Unconjugated
ADAM17 / TACE Antibody (aa1-671) LS-C132358

Mouse Monoclonal (IgG) to Human ADAM17 / TACE
Human
ELISA Flo WB
Unconjugated
ADAM17 / TACE Antibody LS-C659620

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
ELISA IHC WB
Unconjugated
ADAM17 / TACE Antibody (aa670-750) LS-C386303

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
ELISA IF
Unconjugated
ADAM17 / TACE Antibody (aa226-473) LS-C292564
Western blot of recombinant ADAM17 / TACE.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human
IHC WB
Unconjugated
ADAM17 / TACE Antibody LS-C401181
Immunohistochemistry of Human lung cancer using ADAM17 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human lung cancer using ADAM17 Polyclonal Antibody at dilution of 1:15.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
ELISA IHC
Unconjugated
ADAM17 / TACE Antibody LS-C331119
Immunohistochemistry of paraffin-embedded rat heart.
Western blot analysis of extracts of various cell lines.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Rat, Human
IHC WB
Unconjugated
ADAM17 / TACE Antibody (aa701-750) LS-C198590
Immunofluorescence of NIH-3T3 cells, using ADAM 17 Antibody. The sample on the right was incubated with synthetic peptide.

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
IF Peptide-ELISA
Unconjugated
ADAM17 / TACE Antibody (aa807-823) LS-C121111

Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Mouse, Rat, Human
IHC IHC-P
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number