Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-B4426-50 | 50 µg (1 mg/ml) | $440 |
1 of 4
2 of 4
3 of 4
4 of 4
IHC‑plus™ Monoclonal Mouse anti‑Human ADAM17 / TACE Antibody (clone 1F6, IHC, WB) LS‑B4426
IHC‑plus™ Monoclonal Mouse anti‑Human ADAM17 / TACE Antibody (clone 1F6, IHC, WB) LS‑B4426
Note: This antibody replaces LS-C105036
Antibody:
ADAM17 / TACE Mouse anti-Human Monoclonal (1F6) Antibody
Application:
IHC, IHC-P, WB, ELISA, PLA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ADAM17 / TACE Mouse anti-Human Monoclonal (1F6) Antibody
Application:
IHC, IHC-P, WB, ELISA, PLA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
TACE antibody LS-B4426 is an unconjugated mouse monoclonal antibody to human TACE (ADAM17). Validated for ELISA, IHC, PLA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human ADAM17 / TACE
Synonyms
ADAM17 | CD156B | CD156b antigen | CSVP | ADAM 17 | NISBD | TNF-alpha converting enzyme | TNF-alpha convertase | TNF-alpha-converting enzyme | Snake venom-like protease | TACE
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2b,k
Monoclonal
Clone
1F6
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
ADAM17 (NP_003174, 215 aa ~ 315 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (1:500 - 1:1000)
- ELISA
- Proximity Ligation Assay
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western blot performed with the recombinant protein used as the immunogen. In situ Proximity Ligation Assay (Cell).
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADAM17 / TACE
Validation
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ADAM17 / TACE Antibody (clone 1F6) for IHC, WB/Western, ELISA LS-B4426 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance. Jacob J Orme, Khalid A Jazieh, Tiancheng Xie, Susan Harrington, Xin Liu, Matthew Ball, Benjamin Madden, M Cristine Charlesworth, Tariq U Azam, Fabrice Lucien, Bharath Wootla, Yanli Li, Jose Caetano Villasboas, Aaron S Mansfield, Roxana S Dronca, Haidong Dong. Oncoimmunology. 2020 May;9:1744980.
Customer Reviews (0)
Featured Products
Species:
Human, Rat
Applications:
ICC, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
