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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136850-20 | 20 µg | $475 |
| LS-G136850-100 | 100 µg | $1,164 |
| LS-G136850-1 | 1 mg | $2,187 |
Human PRF1 / Perforin Protein (Recombinant MBP, N-terminus + 6His, C-terminus) (Full Length) - LS-G136850
Human PRF1 / Perforin Protein (Recombinant MBP, N-terminus + 6His, C-terminus) (Full Length) - LS-G136850
Description:
PRF1 / Perforin Protein LS-G136850 is a Recombinant Human PRF1 / Perforin produced in Baculovirus 22-555aa with MBP, N-terminus + 6His, C-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
PRF1 / Perforin Protein LS-G136850 is a Recombinant Human PRF1 / Perforin produced in Baculovirus 22-555aa with MBP, N-terminus + 6His, C-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
PRF1 / Perforin
Synonyms
PRF1 | HPLH2 | Perforin | p1 | Perforin1 | PFP | Cytolysin | FLH2 | Perforin-1
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
MBP, N-terminus + 6His, C-terminus
Region
22-555aa
Predicted Molecular Weight
103.2 kDa
AA Sequence
PCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQMLLGEPPGNRSGAVW
Expression System
Baculovirus
Source Species
Baculovirus
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.
Reconstitution
Briefly centrifuge vial prior to opening. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Add 5-50% of glycerol (final concentration).
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PRF1 / Perforin
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular PRF1 / Perforin Proteins
Source:
E. coli
Tag:
His-GST, N-terminus
Source:
E. coli
Tag:
6His, N-terminus
Source:
E. coli
Tag:
His-GST, N-terminus
Source:
Human
Tag:
Myc-DDK (Flag)
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/27/2024
Date Requested: 4/27/2024
