PRF1 / Perforin

perforin 1 (pore forming protein)

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

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Products

Proteins (16)

Type

Over-Expression Lysate (4)

Recombinant (12)

Target

PRF1 / Perforin (16)

Publications

No (16)

Tag

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus (3)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His-GST, N-terminus (2)

His-T7 (1)

MBP, N-terminus + 6His, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (10)

Mouse (2)

Rat (2)

Vibrio vulnificus (1)

Source

293T Cells (2)

Baculovirus (1)

E. coli (8)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (1)

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Human PRF1 / Perforin Protein (Recombinant 6His-SUMO, N-terminus) (aa22-555) - LS-G21075

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

75.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse PRF1 / Perforin Protein (Recombinant His-GST, N-terminus) (Val40-Lys355) - LS-G13648

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

67.2 kDa

Price:

10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453

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Human PRF1 / Perforin Protein (Recombinant 6His, N-terminus) (Pro22-Trp555) - LS-G26593

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

59.2 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human PRF1 / Perforin Protein (Recombinant GST) (Full Length) - LS-G29882

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.48 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PRF1 / Perforin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77955

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.38 kDa

Price:

20 µg/$150

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Human PRF1 / Perforin Protein (Recombinant MBP, N-terminus + 6His, C-terminus) (Full Length) - LS-G136850

Source:

Baculovirus

Tag:

MBP, N-terminus + 6His, C-terminus

Molecular Weight:

103.2 kDa

Price:

100 µg/$1,164; 20 µg/$475; 1 mg/$2,187

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Human PRF1 / Perforin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119797

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.38 kDa

Price:

100 µg/$494

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Rat PRF1 / Perforin Protein (Recombinant 6His, N-terminus) (aa25-554) - LS-G21076

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

62.9 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Mouse PRF1 / Perforin Protein (Recombinant 6His, N-terminus) (aa22-555) - LS-G57239

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Human PRF1 / Perforin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77954

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.38 kDa

Price:

20 µg/$150

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Human PRF1 / Perforin Protein (Recombinant His-GST, N-terminus) (Lys32-Phe316) - LS-G13649

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

63.4 kDa

Price:

10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562

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Vibrio vulnificus PRF1 / Perforin Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (Full Length) - LS-G137212

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

55.8 kDa

Price:

20 µg/$364; 1 mg/$1,679; 100 µg/$500

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PRF1 / Perforin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116230

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.38 kDa

Price:

100 µg/$494

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Human PRF1 / Perforin Protein (Recombinant GST, N-terminus) (aa461-555) - LS-G59711

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PRF1 / Perforin Protein (Recombinant His) (aa247-555) - LS-G140868

Source:

E. coli

Sequence Length:

308 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

33.99 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Rat PRF1 / Perforin Protein (Recombinant His-T7) (aa120-353) - LS-G13650

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.7 kDa

Price:

50 µg/$472; 10 µg/$286; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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