Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recombinant Mouse Interleukin-36 beta is produced by our E. coli expression system and the target gene encoding Ser31-Lys183 is expressed.
Greater than 95% by SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 0.2 µm filtered 20 mM Tris, pH 8.0, 150 mM NaCl, 1 mM EDTA.
Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.
IL36B Protein, FIL1 Protein, FIL1 eta Protein, FILI-(ETA) Protein, IL-1 eta Protein, IL-1F8 Protein, Interleukin 1, eta Protein, Interleukin-1 eta Protein, IL1F8 Protein, Interleukin 36, beta Protein, Interleukin-1 family member 8 Protein, Interleukin-1 Superfamily e Protein, Family of interleukin 1-eta Protein, FIL1H Protein, Interleukin-1 homolog 2 Protein, FIL1-(ETA) Protein, IL-1F8 (FIL1-eta) Protein, IL-1H2 Protein, IL1-ETA Protein, IL1H2 Protein, Interleukin-36 beta Protein
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP.