Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-G49851-50 50 µg $403 
LS-G49851-500 500 µg $1,697 
IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
IL23 Protein
IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
IL23 Protein
1 of 2
2 of 2

Mouse IL23 Protein (Recombinant His,C-terminus) (Met1-Ala196) - LS-G49851

Mouse IL23 Protein (Recombinant His,C-terminus) (Met1-Ala196) - LS-G49851

Description:
IL23 Protein LS-G49851 is a Recombinant Mouse IL23 produced in HEK 293 Cells Met1-Ala196 + Met1-Ser335 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Price
Catalog Number
$403
LS-G49851-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Description:
IL23 Protein LS-G49851 is a Recombinant Mouse IL23 produced in HEK 293 Cells Met1-Ala196 + Met1-Ser335 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only

Specifications

Type
Recombinant Protein
Target
IL23
Synonyms
IL23
Species
Mouse
Modifications
Unmodified
Conjugations
Unconjugated
Applications
  • Binding
  • ELISA
  • Functional Assay
  • Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Ala196 + Met1-Ser335
Predicted Molecular Weight
The recombinant mouse IL23 (mouse IL23A&IL12B Heterodimer) comprises 510 (186+324) amino acids and has a calculated molecular mass of 58.3 (21.1+ 37.2) KDa. The apparent molecular mass of the recombinant protein is approximately 47,45 and 26 KDa respectively in SDS-PAGE under reducing conditions.
Expression System
HEK 293 Cells
Source Species
Human
Purification
(33.1+31.5+32.9) % as determined by SDS-PAGE
Bio-Activity
Measured by its binding ability in a functional ELISA. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee

Publications (0)

Customer Reviews (0)

Images

Binding

IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

IL23 Protein

Binding

IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

IL23 Protein

Binding

IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

IL23 Protein

Binding

IL23 Protein - Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.
Measured by its binding ability in a functional ELISA. 1. Measured by its ability to bind recombinant rat IL23R-Fc in a functional ELISA. 2. Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind human IL23R-Fc. The EC50 of human IL23R-Fc is 0.14-0.35 µg/ml. 3.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 µg/ml. 4.Immobilized mouse IL12Bh (m)+mIL23Ah at 10 µg/ml (100 µl/well) can bind biotinylated human IL12RB1-His. The EC50 of biotinylated human IL12RB1-His is 21.3-49.8 ng/mL. 5. Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 0.5-4ng/mL.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

IL23 Protein

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 6/15/2024