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Mouse GZMB / Granzyme B Recombinant Protein LS-G129

Ordering

Wt. Vol. Conc. Price
2 µg - - $215
10 µg - - $285
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GZMB / Granzyme B Proteins

Human GZMB / Granzyme B Recombinant (His) Protein - LS-G20803
E. coli Expression System
His
Unpurified / Lyophilized
Mouse GZMB / Granzyme B Recombinant Protein - LS-G27274
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).
Mouse GZMB / Granzyme B Recombinant (6His,C-terminus) Protein - LS-G39163
Human Human Cells
6His,C-terminus
Unpurified / Lyophilized

100% Guaranteed 100% Guaranteed
LS-G129
Recombinant Protein
GZMB / Granzyme B
Mouse
28.9 kDa
IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL
TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY
NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD
VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR
YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG
YKDGSPPRAF TKVSSFLSWI KKTMKSS
Baculovirus
Baculovirus
None
Greater than 98% by SDS-PAGE and HPLC
Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity, when using the Ac-IEPD-pNA substrate at 25¦C, is greater than 750 nM/min per ug of enzyme.
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Sterile filtered, lyophilized from 1X PBS
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
If lyophilized, can be stored for 1 month at room temperature, 6 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GZMB / Granzyme B

P10144 NM_004131 NP_004122.2

GZMB Protein, CCPI Protein, CGL-1 Protein, Cathepsin G-like 1 Protein, CSP-B Protein, CTLA-1 Protein, CTLA1 Protein, CGL1 Protein, CSPB Protein, Fragmentin 2 Protein, GRB Protein, HLP Protein, Human lymphocyte protein Protein, Fragmentin-2 Protein, SECT Protein, Lymphocyte protease Protein, T-cell serine protease 1-3E Protein, C11 Protein, CTSGL1 Protein, Cytotoxic serine protease B Protein, Granzyme B Protein, Granzyme-2 Protein

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Requested From: United States
Date Requested: 12/7/2016

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