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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136824-10 | 10 µg | $303 |
| LS-G136824-50 | 50 µg | $453 |
| LS-G136824-500 | 500 µg | $1,987 |
| LS-G136824-1 | 1 mg | $2,837 |
Mouse GPC1 / Glypican Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136824
Mouse GPC1 / Glypican Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136824
Description:
GPC1 / Glypican Protein LS-G136824 is a Recombinant Mouse GPC1 / Glypican produced in Mammalian Cells 24-529aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
GPC1 / Glypican Protein LS-G136824 is a Recombinant Mouse GPC1 / Glypican produced in Mammalian Cells 24-529aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
GPC1 / Glypican
Synonyms
GPC1 | Glypican 1 | Glypican | Glypican-1 | Glypican proteoglycan 1
Species
Mouse
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, C-terminus
Region
24-529aa
Predicted Molecular Weight
56.7 kDa
AA Sequence
DPASKSRSCSEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENLANHSRMELESALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAPECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGNPKVNPHGSGPEEKRRRGKLALQEKPSTGTLEKLVSEAKAQLRDIQDFWISLPGTLCSEKMAMSPASDDRCWNGISKGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRGAYGGNDVDFQDASDDGSGSGSGGGCPDDTCGRRVSKKSSSSRTPLTHALPGLSEQEGQKTS
Expression System
Mammalian Cells
Source Species
Mammal
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Binds Cu(2+) or Zn(2+) ions.
Bio-Activity
The ED50 as determined by its ability to bind Human FGFb in functional ELISA is less than 10 ug/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered PBS, pH 7.4
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GPC1 / Glypican
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular GPC1 / Glypican Proteins
Source:
Human
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/7/2024
Date Requested: 5/7/2024
