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Mouse CASP8 / Caspase 8 Protein (Recombinant) (Ser219-Pro480) - LS-G26673

Catalog Size Price
LS-G26673-200 200 µg Unavailable

Most Popular CASP8 / Caspase 8 Proteins

Human CASP8 / Caspase 8 Protein (Recombinant 6His,N-terminus) (aa215-478) - LS-G4183
E. coli Expression System
6His,N-terminus
Purified / Lyophilized / Biologically Active
Mouse CASP8 / Caspase 8 Protein (Recombinant 6His,N-terminus) - LS-G4197
E. coli Expression System
6His,N-terminus
Purified / Lyophilized / Biologically Active
Bovine CASP8 / Caspase 8 Protein (Recombinant His) (aa25-175) - LS-G12987
E. coli Expression System
His
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human CASP8 / Caspase 8 Protein (Recombinant His + T7) (aa102-345) - LS-G12988
E. coli Expression System
His + T7
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Rat CASP8 / Caspase 8 Protein (Recombinant His + T7) (aa8-197) - LS-G24142
E. coli Expression System
His + T7
Lyophilized

100% Guaranteed
LS-G26673
Recombinant Protein
CASP8 / Caspase 8
Mouse
30 kDa
Ser219-Pro480
HEK 293 Cells
Human
None
Not Tested
Not Tested
Lyophilized from 0.2 µm filtered PBS, protease inhibitors.
Centrifuge the vial before opening. Reconstitute in sterile deionized water or PBS to 0.5-1 mg/ml.
Store lyophilized at -20°C. After reconstitution, aliquot and store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About CASP8 / Caspase 8

Q14790 nm_001228 AAC50645.1

CASP8 Protein, ALPS2B Protein, Apoptotic protease Mch-5 Protein, Apoptotic cysteine protease Protein, Casp-8 Protein, Caspase-8 Protein, CAP4 Protein, Caspase 8 Protein, MACH Protein, MCH5 Protein, MORT1-associated ced-3 homolog Protein, ICE-like apoptotic protease 5 Protein, Pro Caspase 8 Protein, FADD-like ICE Protein, FLICE Protein, MACH-alpha-1/2/3 protein Protein, MACH-beta-1/2/3/4 protein Protein

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases.

Requested From: 
Date Requested: 8/20/2017

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