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Mouse CASP8 / Caspase 8 Protein (Over-Expression Cell Culture Supernatant 6His,N-terminus) (Ser219-Pro480) - LS-G26673

Catalog Size Price
LS-G26673-100 100 µg Unavailable

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Mouse CASP8 / Caspase 8 Protein (Over-Expression Cell Culture Supernatant 6His,N-terminus) (Ser219-Pro480) - LS-G26822
Human HEK 293 Cells

100% Guaranteed
Over-Expression Cell Culture Supernatant Protein
CASP8 / Caspase 8
30 kDa
This product is serum free.
HEK 293 Cells
Not Tested
Not Tested
Lyophilized from 0.2 µm filtered PBS, protease inhibitors.
Centrifuge the vial before opening. Reconstitute in sterile deionized water or PBS to 0.5-1 mg/ml.
Store lyophilized at -20°C. After reconstitution, aliquot and store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About CASP8 / Caspase 8

Q14790 nm_001228 AAC50645.1

CASP8 Protein, ALPS2B Protein, Apoptotic protease Mch-5 Protein, Apoptotic cysteine protease Protein, Casp-8 Protein, Caspase-8 Protein, CAP4 Protein, Caspase 8 Protein, MACH Protein, MCH5 Protein, MORT1-associated ced-3 homolog Protein, ICE-like apoptotic protease 5 Protein, Pro Caspase 8 Protein, FADD-like ICE Protein, FLICE Protein, MACH-alpha-1/2/3 protein Protein, MACH-beta-1/2/3/4 protein Protein

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases.

Requested From: 
Date Requested: 4/19/2018

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