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Human ZAP70 Recombinant (GST) Protein LS-G30929

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
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LS-G30929
Recombinant Protein
ZAP70
Human
79.97 kDa
MRLGPRWKGE ALEQAIISQA PQVEKLIATT AHERMPWYHS
SLTREEAERK LYSGAQTDGK FLLRPRKEQG TYALSLIYGK
TVYHYLISQD KAGKYCIPEG TKFDTLWQLV EYLKLKADGL
IYCLKEACPN SSASNASGAA APTLPAHPST LTHPQRRIDT
LNSDGYTPEP ARITSPDKPR PMPMDTSVYE SPYSDPEELK
DKKLFLKRDN LLIADIELGC GNFGSVRQGV YRMRKKQIDV
AIKVLKQGTE KADTEEMMRE AQIMHQLDNP YIVRLIGVCQ
AEALMLVMEM AGGGPLHKFL VGKREEIPVS NVAELLHQVS
MGMKYLEEKN FVHRDLAARN VLLVNRHYAK ISDFGLSKAL
GADDSYYTAR SAGKWPLKWY APECINFRKF SSRSDVWSYG
VTMWEALSYG QKPYKKMKGP EVMAFIEQGK RMECPPECPP
ELYALMSDCW IYKWEDRPDF LTVEQRMRAC YYSLASKVEG
PPGSTQKAEA ACA
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About ZAP70

P43403 NM_207519 P43403

ZAP70 Protein, 70 kDa zeta-associated protein Protein, SRK Protein, STCD Protein, STD Protein, Syk-related tyrosine kinase Protein, Tyrosine-protein kinase ZAP-70 Protein, TZK Protein, ZAP-70 Protein, Zeta-associated protein 70 Protein

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human ZAP70 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/5/2016

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