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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136728-10 | 10 µg | $356 |
| LS-G136728-50 | 50 µg | $698 |
| LS-G136728-500 | 500 µg | $1,987 |
| LS-G136728-1 | 1 mg | $2,837 |
Human TNFSF11 / RANKL / TRANCE Protein (Recombinant 6His, N-terminus) - LS-G136728
Human TNFSF11 / RANKL / TRANCE Protein (Recombinant 6His, N-terminus) - LS-G136728
Description:
TNFSF11 / RANKL / TRANCE Protein LS-G136728 is a Recombinant Human TNFSF11 / RANKL / TRANCE produced in E. coli 140-317aa with 6His, N-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
TNFSF11 / RANKL / TRANCE Protein LS-G136728 is a Recombinant Human TNFSF11 / RANKL / TRANCE produced in E. coli 140-317aa with 6His, N-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TNFSF11 / RANKL / TRANCE
Synonyms
TNFSF11 | CD254 | CD254 antigen | HRANKL2 | OPTB2 | TRANCE | ODF | OPGL | SOdf | Osteoprotegerin ligand | RANKL
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, N-terminus
Region
140-317aa
Predicted Molecular Weight
22.4 kDa
AA Sequence
IRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy
Bio-Activity
The ED50 as determined by its ability to binding SF11A used funtional ELISA is less than 10 ug/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFSF11 / RANKL / TRANCE
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/2/2024
Date Requested: 5/2/2024
