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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136730-10 | 10 µg | $313 |
| LS-G136730-50 | 50 µg | $516 |
| LS-G136730-500 | 500 µg | $1,987 |
| LS-G136730-1 | 1 mg | $2,837 |
Human TNFRSF1B / TNFR2 Protein (Recombinant 6His, C-terminus) - LS-G136730
Human TNFRSF1B / TNFR2 Protein (Recombinant 6His, C-terminus) - LS-G136730
Description:
TNFRSF1B / TNFR2 Protein LS-G136730 is a Recombinant Human TNFRSF1B / TNFR2 produced in Mammalian Cells 23-257aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
TNFRSF1B / TNFR2 Protein LS-G136730 is a Recombinant Human TNFRSF1B / TNFR2 produced in Mammalian Cells 23-257aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TNFRSF1B / TNFR2
Synonyms
TNFRSF1B | CD120b antigen | CD120b | p75 TNF receptor | Soluble TNFR1B variant 1 | TNFBR | Tumor necrosis factor receptor | TNF-R-II | TNF-R75 | TNFR2 | p75TNFR | p80 TNF-alpha receptor | TBPII | TNF-R2 | TNFR80 | TNF-RII | TNFR-II | TNFR1B
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, C-terminus
Region
23-257aa
Predicted Molecular Weight
26.2 kDa
AA Sequence
LPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGD
Expression System
Mammalian Cells
Source Species
Mammal
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Bio-Activity
The ED50 as determined by its ability to inhibit TNFa-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TNFa is less than 0.6 µg/mL.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered 20 mM PBs, pH 7.4, 150 mM NaCl
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFRSF1B / TNFR2
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular TNFRSF1B / TNFR2 Proteins
Source:
E. coli
Tag:
His, N-Terminal
Source:
Human
Tag:
Fc, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/6/2024
Date Requested: 5/6/2024
