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Human TICAM2 / TRAM Recombinant (GST) Protein LS-G37360

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TICAM2 / TRAM Proteins

Human TICAM2 / TRAM Recombinant (His) Protein - LS-G1622
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human TICAM2 / TRAM Recombinant (His + T7) Protein - LS-G15818
E. coli Expression System
His + T7
Unpurified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human TICAM2 / TRAM Recombinant (His) Protein - LS-G18684
E. coli Expression System
His
Unpurified / Lyophilized

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LS-G37360
Recombinant Protein
TICAM2 / TRAM
Human
53.3 kDa
MGIGKSKINS CPLSLSWGKR HSVDTSPGYH ESDSKKSEDL
SLCNVAEHSN TTEGPTGKQE GAQSVEEMFE EEAEEEVFLK
FVILHAEDDT DEALRVQNLL QDDFGIKPGI IFAEMPCGRQ
HLQNLDDAVN GSAWTILLLT ENFLRDTWCN FQFYTSLMNS
VNRQHKYNSV IPMRPLNNPL PRERTPFALQ TINALEEESR
GFPTQVERIF QESVYKTQQT IWKETRNMVQ RQFIA
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About TICAM2 / TRAM

Q86XR7 NM_021649 NP_067681.1

TICAM2 Protein, Cytoplasmic adaptor Protein, TRIF-related adapter molecule Protein, TIRAP3 Protein, TRIF-related adaptor molecule Protein, TICAM-2 Protein, TIRP Protein, TRAM Protein

Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human TICAM2 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/8/2016

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