Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SNAI1 Protein, DJ710H13.1 Protein, Protein sna Protein, SNAIL Protein, Snail 1 Protein, Snail 1, zinc finger protein Protein, Snail homolog 1 (Drosophila) Protein, SNA Protein, Snail 1 homolog Protein, Protein snail homolog 1 Protein, SNAH Protein, Snail 1 zinc finger protein Protein, Zinc finger protein SNAI1 Protein, SLUGH2 Protein, SNAIL1 Protein
Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription.