Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SMG5 Protein, EST1-like protein B Protein, EST1B Protein, Ever shorter telomeres 1B Protein, Est1p-like protein B Protein, LPTS-RP1 Protein, LPTS interacting protein Protein, KIAA1089 Protein, Protein SMG5 Protein, RP11-54H19.7 Protein, SMG-5 Protein, HSMG-5 Protein, LPTS-interacting protein Protein, LPTSRP1 Protein, SMG-5 homolog Protein
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.