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SMG5

SMG5 nonsense mediated mRNA decay factor

Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.

Gene Name:	SMG5 nonsense mediated mRNA decay factor
Synonyms:	SMG5, EST1-like protein B, EST1B, Ever shorter telomeres 1B, Est1p-like protein B, LPTS-RP1, LPTS interacting protein, KIAA1089, Protein SMG5, RP11-54H19.7, SMG-5, HSMG-5, LPTS-interacting protein, LPTSRP1, SMG-5 homolog
Target Sequences:	T65307

SMG5 Protein - 12.5% SDS-PAGE of human SMG5 stained with Coomassie Blue

Human SMG5 Protein (Recombinant GST) (Full Length) - LS-G32818

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

140.3 kDa

Price:

10 µg/$479; 25 µg/$670

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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