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Human SHARPIN Recombinant (GST) Protein LS-G35540

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SHARPIN Proteins

Human SHARPIN Recombinant (GST) Protein - LS-G35540
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G35540
Recombinant Protein
SHARPIN
Human
60.3 kDa
MAPPAGGAAA AASDLGSAAV LLAVHAAVRP LGAGPDAEAQ
LRRLQLSADP ERPGRFRLEL LGAGPGAVNL EWPLESVSYT
IRGPTQHELQ PPPGGPGTLS LHFLNPQEAQ RWAVLVRGAT
VEGQNGSKSN SPPALGPEAC PVSLPSPPEA STLKGPPPEA
DLPRSPGNLT EREELAGSLA RAIAGGDEKG AAQVAAVLAQ
HRVALSVQLQ EACFPPGPIR LQVTLEDAAS AASAASSAHV
ALQVHPHCTV AALQEQVFSE LGFPPAVQRW VIGRCLCVPE
RSLASYGVRQ DGDPAFLYLL SAPREAPAQL VLSFLHLHQC
PRPPWL
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About SHARPIN

Q9H0F6 NM_030974 NP_112236.3

SHARPIN Protein, DKFZP434N1923 Protein, SIPL1 Protein, HSIPL1 Protein

Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human SHARPIN stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/5/2016

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