Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recombinant Human S100A8 & S100A9 Heterodimer is produced by our E. coli expression system and the target gene encoding Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus.
Met1-Glu93(S100A8) + Thr2-Pro114(S100A9)
Greater than 95% by SDS-PAGE
Less than 0.1 EU/µg protein (determined by LAL method).
Store at < -20°C, stable for 6 months after receipt. Minimize freeze-thaw cycles.
S100A8 Protein, 60B8AG Protein, CFAG Protein, CAGA Protein, Calgranulin A Protein, Calgranulin-A Protein, Calprotectin L1L subunit Protein, Cystic fibrosis antigen Protein, CGLA Protein, L1Ag Protein, NIF Protein, p8 Protein, Protein S100-A8 Protein, MRP8 Protein, Urinary stone protein band A Protein, CP-10 Protein, MA387 Protein, MRP-8 Protein
S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.