Target
PD-L2 / PDCD1LG2 / CD273
Synonyms
PDCD1LG2 | B7 dendritic cell molecule | B7-DC | B7DC | BA574F11.2 | CD273 | Btdc | CD273 antigen | PD-L2 | PDCD1 ligand 2 | PD-1-ligand 2 | Programmed death ligand 2 | Butyrophilin B7-DC | PD-1 ligand 2 | PDCD1L2 | PDL2
Modifications
Unmodified.
Also available
Preservative Free.
Conjugations
Unconjugated.
Also available conjugated with
Biotin.
Region
Mature extracellular region of CD273EC.
Predicted Molecular Weight
49 kDa
AA Sequence
lftvtvpkelyiiehgsnvtlecnfdtgshvnlgaitaslqkvendtsphreratlleeqlplgkasfhipqvqvrdegqyqciiiygvawdykyltlkvkasyrkinthilkvpetdeveltcqatgyplaevswpnvsvpantshsrtpeglyqvtsvlrlkpppgrnfscvfwnthvreltlasidlqsqmeprthpt
Expression System
CHO Cells
Source Species
Hamster-Chinese
Usage Summary
A soluble fusion protein consisting of the Mature extracellular region of CD273EC: (20)lftvtvpkelyiiehgsnvtlecnfdtgshvnlgaitaslqkvendtsphreratlleeqlplgkasfhipqvqvrdegqyqciiiygvawdykyltlkvkasyrkinthilkvpetdeveltcqatgyplaevswpnvsvpantshsrtpeglyqvtsvlrlkpppgrnfscvfwnthvreltlasidlqsqmeprthpt (220) Linker + Murine IgG2a Hinge + Fc: (221)gteprgptikpcppckcpapnllggpsvfifppkikdvlmislspivtcvvvdvseddpdvqiswfvnnvevhtaqtqthredynstlrvvsalpiqhqdwmsgkefkckvnnkdlpapiertiskpkgsvrapqvyvlpppeeemtkkqvtvtcmvtdfmpediyvewtnngktelnykntepvldsdgsyfmysklgvekknwvernsyscsvvheglhnhhttksfsrtpg(455). Predicted monomeric (non glycosylated) molecular weight: 49 kd. The molecule is dimeric and runs at ~135 kd in SDS-PAGE under native conditions, and ~74 kd reduced. N-terminal sequence was as predicted: LFTVT Recombinant CD273-muIg was detectable at 50 ng/ml in EIA using Goat-anti-Mouse-IgG coated plate for capture and recombinant CD279 /Biotin followed by SA/HRP as detection reagents.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.5 mg/ml Gentamicin Sulfate
Storage
Store at 2°C to 5°C for up to 6 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About PD-L2 / PDCD1LG2 / CD273