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Human OTUB1 / OTU1 Recombinant (His) Protein LS-G575

Ordering

Wt. Vol. Conc. Price
100 µg - - $315
500 µg - - $680
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular OTUB1 / OTU1 Proteins

Human OTUB1 / OTU1 Recombinant (His) Protein - LS-G575
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human OTUB1 / OTU1 Recombinant (His) Protein - LS-G20109
E. coli Expression System
His
Unpurified / Lyophilized
Human OTUB1 / OTU1 Recombinant (GST) Protein - LS-G22218
E. coli Expression System
GST
Unpurified / Lyophilized

100% Guaranteed 100% Guaranteed
LS-G575
Recombinant Protein
OTUB1 / OTU1
Human
MGSSHHHHHH SSGLVPRGSH MAAEEPQQQK QEPLGSDSEG
VNCLAYDEAI MAQQDRIQQE IAVQNPLVSE RLELSVLYKE
YAEDDNIYQQ KIKDLHKKYS YIRKTRPDGN CFYRAFGFSH
LEALLDDSKE LQRFKAVSAK SKEDLVSQGF TEFTIEDFHN
TFMDLIEQVE KQTSVADLLA SFNDQSTSDY LVVYLRLLTS
GYLQRESKFF EHFIEGGRTV KEFCQQEVEP MCKESDHIHI
IALAQALSVS IQVEYMDRGE GGTTNPHIFP EGSEPKVYLL
YRPGHYDILY K
E. coli
E. coli
His
Greater than 95% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 10% glycerol
For research use only.

About OTUB1 / OTU1

Q96FW1 NM_017670 NP_060140.2

OTUB1 Protein, Deubiquitinating enzyme OTUB1 Protein, HSPC263 Protein, HOTU1 Protein, OTU-domain Ubal-binding 1 Protein, OTU1 Protein, Otubain-1 Protein, Ubiquitin thioesterase OTUB1 Protein, OTB1 Protein

Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy. Isoform 1 destabilizes RNF128, leading to prevent anergy.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 
 

Requested From: United States
Date Requested: 12/2/2016

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