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Human OTUB1 / OTU1 Protein (Recombinant GST) (Full Length) - LS-G22218

Catalog Size Price
LS-G22218-50 50 µg Unavailable
LS-G22218-200 200 µg Unavailable
LS-G22218-500 500 µg Unavailable
LS-G22218-1000 1000 µg Unavailable

Most Popular OTUB1 / OTU1 Proteins

Human OTUB1 / OTU1 Protein (Recombinant His) - LS-G575
E. coli Expression System
291 AA
His
Purified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Rat OTUB1 / OTU1 Protein (Recombinant His) (aa1-271) - LS-G16172
E. coli Expression System
His
Purified / Lyophilized
Mouse OTUB1 / OTU1 Protein (Recombinant His) (aa1-271) - LS-G16173
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Purified / Lyophilized
Human OTUB1 / OTU1 Protein (Recombinant His) (aa1-271) - LS-G16175
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His
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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human OTUB1 / OTU1 Protein (Recombinant His) - LS-G20109
E. coli Expression System
His
Purified

100% Guaranteed
LS-G22218
Recombinant Protein
OTUB1 / OTU1
Human
50.5 kD Full Length
aa 2-201
AAEEPQQQKQ EPLGSDSEGV NCLAYDEAIM AQQDRIQQEI
AVQNPLVSER LELSVLYKEY AEDDNIYQQK IKDLHKKYSY
IRKTRPDGNC FYRAFGFSHL EALLDDSKEL QRFKAVSAKS
KEDLVSQGFT EFTIEDFHNT FMDLIEQVEK QTSVADLLAS
FNDQSTSDYL VVYLRLLTSG YLQRESKFFE HFIEGGRTVK
E. coli
E. coli
GST
Not Tested
Not Tested
Tris buffer, 50% glycerol.
Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
For research use only.

About OTUB1 / OTU1

Q96FW1 NM_017670 NP_060140.2

OTUB1 Protein, Deubiquitinating enzyme OTUB1 Protein, HSPC263 Protein, HOTU1 Protein, OTU-domain Ubal-binding 1 Protein, OTU1 Protein, Otubain-1 Protein, Ubiquitin thioesterase OTUB1 Protein, OTB1 Protein

Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy. Isoform 1 destabilizes RNF128, leading to prevent anergy.

Requested From: 
Date Requested: 10/18/2017

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