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Human NAE1 / APPBP1 Recombinant (His) Protein LS-G1576

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
250 µg - 0.5 mg/ml $905
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NAE1 / APPBP1 Proteins

Human NAE1 / APPBP1 Recombinant (His) Protein - LS-G1576
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human NAE1 / APPBP1 Recombinant (His) Protein - LS-G17447
E. coli Expression System
His
Unpurified / Lyophilized
Human NAE1 / APPBP1 Recombinant (GST) Protein - LS-G31386
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G1576
Recombinant Protein
NAE1 / APPBP1
Human
MGSSHHHHHH SSGLVPRGSH MGSMAQLGKL LKEQKYDRQL
RLWGDHGQEA LESAHVCLIN ATATGTEILK NLVLPGIGSF
TIIDGNQVSG EDAGNNFFLQ RSSIGKNRAE AAMEFLQELN
SDVSGSFVEE SPENLLDNDP SFFCRFTVVV ATQLPESTSL
RLADVLWNSQ IPLLICRTYG LVGYMRIIIK EHPVIESHPD
NALEDLRLDK PFPELREHFQ SYDLDHMEKK DHSHTPWIVI
IAKYLAQWYS ETNGRIPKTY KEKEDFRDLI RQGILKNENG
APEDEENFEE AIKNVNTALN TTQIPSSIED IFNDDRCINI
TKQTPSFWIL ARALKEFVAK EGQGNLPVRG TIPDMIADSG
KYIKLQNVYR EKAKKDAAAV GNHVAKLLQS IGQAPESISE
KELKLLCSNS AFLRVVRCRS LAEEYGLDTI NKDEIISSMD
NPDNEIVLYL MLRAVDRFHK QQGRYPGVSN YQVEEDIGKL
KSCLTGFLQE YGLSVMVKDD YVHEFCRYGA AEPHTIAAFL
GGAAAQEVIK IITKQFVIFN NTYIYSGMSQ TSATFQL
E. coli
E. coli
His
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 200 mM NaCl, 10% glycerol, 2 mM DTT
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About NAE1 / APPBP1

Q13564 NM_003905 NP_003896.1

NAE1 Protein, A-116A10.1 Protein, APPBP1 Protein, HPP1 Protein, Proto-oncogene protein 1 Protein, APP-BP1 Protein, Ula-1 Protein, Protooncogene protein 1 Protein

Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 
 

Requested From: United States
Date Requested: 12/2/2016

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