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Human KLRB1 / CD161 Recombinant (Fc,C-terminus) Protein LS-G40026

Ordering

Wt. Vol. Conc. Price
- 10 µl - $265
- 50 µl - $465
- 500 µl - $1,605
- 1000 µl - $2,520
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KLRB1 / CD161 Proteins

Human KLRB1 / CD161 Recombinant (His) Protein - LS-G1896
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human KLRB1 / CD161 Recombinant (His) Protein - LS-G18852
E. coli Expression System
His
Unpurified / Lyophilized
Human KLRB1 / CD161 Recombinant (Fc,C-terminus) Protein - LS-G40026
Human Human Cells
Fc,C-terminus
Unpurified

100% Guaranteed 100% Guaranteed
LS-G40026
Recombinant Protein
KLRB1 / CD161
Human
Recombinant Human KLRB1 is produced by our Mammalian expression system and the target gene encoding Gln67-Ser225 is expressed with a Fc tag at the C-terminus.
Gln67-Ser225
QKSSIEKCSV DIQQSRNKTT ERPGLLNCPI YWQQLREKCL
LFSHTVNPWN NSLADCSTKE SSLLLIRDKD ELIHTQNLIR
DKAILFWIGL NFSLSEKNWK WINGSFLNSN DLEIRGDAKE
NSCISISQTS VYSEYCSTEI RWICQKELTP VRNKVYPDSV
DDIEGRMDEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP
KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA
KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA
LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC
LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY
SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK
Human Cells
Human
Fc,C-terminus
Lyophilized
For research use only.

About KLRB1 / CD161

Q12918 NM_002258 NP_002249.1

KLRB1 Protein, CD161 antigen Protein, CLEC5B Protein, CD161 Protein, NKR-P1A Protein, NKR Protein, HNKR-P1A Protein, NKR-P1 Protein, NKRP1A Protein

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Requested From: United States
Date Requested: 12/8/2016

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