Target
IL7R / CD127
Synonyms
IL7R | CD127 | CD127 antigen | IL-7RA | IL-7 receptor subunit alpha | IL7RA | ILRA | Interleukin 7 receptor | CDW127 | IL-7R subunit alpha | IL-7R-alpha
Modifications
Unmodified.
Also available
Preservative Free.
Conjugations
Unconjugated
Region
Murine CD8 alpha signal peptide residual amino acids and linker.
Predicted Molecular Weight
52.8 kDa
AA Sequence
esgyaqngdledaelddysfscysqlevngsqhsltcafedpdvnitnlefeicgalvevkclnfrklqeiyfietkkflligksnicvkvgeksltckkidlttivkpeapfdlsvvyregandfvvtfntshlqkkyvkvlmhdvayrqekdenkwthvnlsstkltllqrklqpaamyeikvrsipdhyfkgfwsewspsyyfrtpeinnssgemd
Expression System
CHO Cells
Source Species
Hamster-Chinese
Usage Summary
A soluble molecule consisting of murine CD8 alpha signal peptide residual amino acids and linker: (1)kpqapelrgs(10), the mature extracellular domain of human CD127 (IL-7Ra): (11)esgyaqngdledaelddysfscysqlevngsqhsltcafedpdvnitnlefeicgalvevkclnfrklqeiyfietkkflligksnicvkvgeksltckkidlttivkpeapfdlsvvyregandfvvtfntshlqkkyvkvlmhdvayrqekdenkwthvnlsstkltllqrklqpaamyeikvrsipdhyfkgfwsewspsyyfrtpeinnssgemd(229), murine IgG2a Fc + hinge regions: (230)gteprgptikpcppckcpapnllggpsvfifppkikdvlmislspivtcvvvdvseddpdvqiswfvnnvevhtaqtqthredynstlrvvsalpiqhqdwmsgkefkckvnnkdlpapiertiskpkgsvrapqvyvlpppeeemtkkqvtltcmvtdfmpediyvewtnngktelnykntepvldsdgsyfmysklrvekknwvernsyscsvvheglhnhhttksfsrtpgk(464) (464 aa total). The molecule is dimeric with a predicted monomeric non glycosylated molecular weight of 52.8 kd. Recombinant soluble CD127-muIg was reactive with anti-CD127 clone 40131 as well as clone ANC8F2 in EIA and FACS.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.5 mg/ml Gentamicin Sulfate
Storage
Store at 2°C to 5°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee