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Human DKK2 Recombinant (Fc,N-terminus + 6His,C-terminus) Protein (Asp251-Ile526) - LS-G39397

Ordering

Wt. Vol. Conc. Price
10 µg - - Unavailable
50 µg - - Unavailable
500 µg - - Unavailable
1000 µg - - Unavailable

Most Popular DKK2 Proteins

Human DKK2 Recombinant (His) Protein - LS-G1918
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250 AA
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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human DKK2 Recombinant (His) Protein (aa159-258) - LS-G13243
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Human DKK2 Recombinant (His) Protein - LS-G18870
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Human DKK2 Recombinant (His + SUMO) Protein (aa34-259) - LS-G21931
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226 AA
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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human DKK2 Recombinant (Fc,N-terminus + 6His,C-terminus) Protein (Asp251-Ile526) - LS-G39397
Human Human Cells
517 AA
Fc,N-terminus + 6His,C-terminus
Purified / Lyophilized / Endotoxin Level: Less than 0.1 EU/µg protein (determined by LAL method).

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LS-G39397
Recombinant Protein
DKK2
Human
58.9kD
Recombinant Human Dickkopf-related protein 2 is produced by our Mammalian expression system and the target gene encoding Asp251-Ile526 is expressed with a Fc tag at the N-terminus, 6His tag at the C-terminus.
Asp251-Ile526
EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR
TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ
YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT
ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS
DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS
RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKVDGGGSGG
GSGGGSRKRR MAALMRSKDS SCCLLLLAAV LMVESSQIGS
SRAKLNSIKS SLGGETPGQA ANRSAGMYQG LAFGGSKKGK
NLGQAYPCSS DKECEVGRYC HSPHQGSSAC MVCRRKKKRC
HRDGMCCPST RCNNGICIPV TESILTPHIP ALDGTQHRDR
NHGHYSNHDL GWQNLGRPHT KMSHIKGHEG DPCLRSSDCI
EGFCCARHFW TKICKPVLHQ GEVCTKQRKK GSHGLEIFQR
CDCAKGLSCK VWKDATYSSK ARLHVCQKIV DHHHHHH
Human Cells
Human
Fc,N-terminus + 6His,C-terminus
Greater than 95% by SDS-PAGE
Less than 0.1 EU/µg protein (determined by LAL method).
Lyophilized
Lyophilized protein should be stored at < -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
For research use only.

About DKK2

Q9UBU2 NM_014421 NP_055236.1

DKK2 Protein, DKK-2 Protein, Dickkopf homolog 2 Protein, Dickkopf related protein-2 Protein, HDkk-2 Protein, Dickkopf-2 Protein, Dickkopf-related protein 2 Protein

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Requested From: 
Date Requested: 4/24/2017

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