Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Purified / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Human CCL5 / RANTES Recombinant Protein - LS-G3674
E. coli Expression System
Purified / Lyophilized / Biologically Active / Animal-Free / Endotoxin Level: Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
CCL5 / RANTES
Greater than 98% by SDS-PAGE and HPLC
Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
If lyophilized, can be stored for 1 month at room temperature, 6 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid repeat freeze-thaw cycles.
CCL5 Protein, Chemokine (C-C motif) ligand 5 Protein, D17S136E Protein, EoCP Protein, T-cell specific protein p288 Protein, SCYA5 Protein, SISd Protein, T cell-specific protein P228 Protein, Beta-chemokine RANTES Protein, C-C motif chemokine 5 Protein, RANTES Protein, SIS-delta Protein, Small-inducible cytokine A5 Protein, T-cell-specific protein RANTES Protein, TCP228 Protein
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).