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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
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866-206-6909 (Toll Free North America)
206-577-4565 (International)
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PathPlusTM AMACR / P504S Antibodies
AMACR/P504S is a mitochondrial and peroxisomal enzyme that is overexpressed in prostate cancer and premalignant prostatic lesions including intraepithelial neoplasia and atypical adenomatous hyperplasia. AMACR overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma. AMACR functions to oxidize fatty acids, drugs such as ibuprofen, and bile acid intermediates. It is broadly expressed in normal tissues such as kidney and liver, with a cytoplasmic distribution. AMACR is positive in prostate carcinoma and negative or weak in normal or hyperplastic prostate. The American journal of surgical pathology. 2001. 25.11: 1397-1404, PMID: 11684956 ; Urology. 77 (1): 249.e1–7, PMID: 21195844; Am. J. Surg. Pathol. 27 (6): 772–8, PMID: 12766580.

1 PathPlusTM Antibody
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AMACR / P504S Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
Rabbit Recombinant Monoclonal [clone AMACR/2748R] (IgG) to Human AMACR / P504S
Human
IHC-P
Unconjugated
100µg   200µg/ml   $462.00

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