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Catalog Number Size Price
LS-B16306-100 100 µg (200 µg/ml) $485 
AMACR / P504S Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - SDS-PAGE Analysis Purified Recombinant Rabbit Monoclonal Antibody (AMACR/2748R)Confirmation of Purity and Integrity of Antibody.
AMACR / P504S Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
AMACR / P504S Antibody - SDS-PAGE Analysis Purified Recombinant Rabbit Monoclonal Antibody (AMACR/2748R)Confirmation of Purity and Integrity of Antibody.
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PathPlus™ Recombinant Monoclonal Rabbit anti‑Human AMACR / P504S Antibody (clone AMACR/2748R, aa 297‑394, IHC) LS‑B16306

PathPlus™ Recombinant Monoclonal Rabbit anti‑Human AMACR / P504S Antibody (clone AMACR/2748R, aa 297‑394, IHC) LS‑B16306

Note: This antibody replaces LS-C751143
Antibody:
AMACR / P504S Rabbit anti-Human Recombinant Monoclonal (aa 297-394) (AMACR/2748R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$485
LS-B16306-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
AMACR / P504S Rabbit anti-Human Recombinant Monoclonal (aa 297-394) (AMACR/2748R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
AMACR/P504S is a mitochondrial and peroxisomal enzyme that is overexpressed in prostate cancer and premalignant prostatic lesions including intraepithelial neoplasia and atypical adenomatous hyperplasia. AMACR overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma. AMACR functions to oxidize fatty acids, drugs such as ibuprofen, and bile acid intermediates. It is broadly expressed in normal tissues such as kidney and liver, with a cytoplasmic distribution. AMACR is positive in prostate carcinoma and negative or weak in normal or hyperplastic prostate. References: The American journal of surgical pathology. 2001. 25.11: 1397-1404, PMID: 11684956 ; Urology. 77 (1): 249.e1–7, PMID: 21195844; Am. J. Surg. Pathol. 27 (6): 772–8, PMID: 12766580.
Target
Human AMACR / P504S
Synonyms
AMACR | 2-methylacyl-CoA racemase | AMACRD | Alpha-methylacyl-CoA racemase | CBAS4 | RACE | RM | AMACR/p504S
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Recombinant Monoclonal
Clone
AMACR/2748R
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified. Also available Azide-free, Carrier-free.
Immunogen
Recombinant human AMACR protein fragment (around aa 297-394). Antigen Molecular Weight: 42 kDa
Epitope
aa 297-394
Specificity
This antibody recognizes human AMACR (p504S), a 42 kDa enzyme that is essential for lipid metabolism.
Applications
  • IHC - Paraffin (1:100)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AMACR / P504S
Q9UHK6 NM_014324 NP_055139.4

Validation

AMACR / P504S Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

AMACR / P504S Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

AMACR / P504S Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ AMACR / P504S Antibody (aa 297-394, clone AMACR/2748R) for IHC LS-B16306 has an LSBio Rating of
Laboratory Validation Score (5)

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/17/2021