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PathPlus™ PLIN2 / ADFP / Adipophilin Antibody Polyclonal IHC,WB LS‑B4850

Catalog Number Size Price
LS-B4850-50 50 µl (1 mg/ml) $425 
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. ADFP antibody diluted at 1:1000.
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. ADFP antibody diluted at 1:1000.
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PathPlus™ PLIN2 / ADFP / Adipophilin Antibody Polyclonal IHC,WB LS‑B4850

Note: This antibody replaces LS-C109437
Antibody:
Rabbit Polyclonal to Human PLIN2 / ADFP / Adipophilin
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B4850-50
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human PLIN2 / ADFP / Adipophilin
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
PLIN2 (ADFP, Adipophilin) belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in the development and maintenance of adipose tissue. It is found in the cytoplasm and membrane of a wide range of cultured cell lines and tissues, including fibroblasts, endothelial and epithelial cells, lactating mammary glands, the adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis. Higher levels of PLIN 2 are associated with diabetes, atherosclerosis, sarcopenia, cardiovascular diseases, atherosclerosis, as well as lung, colorectal and Burkitt cancer. In clear cell renal cell carcinoma, high levels of PLIN2 are associated with survival and it is a potential prognostic marker for the disease. In immunohistochemistry, it is considered a useful marker of cytoplasmic lipids, sebocytes, and lipid accumulation, and can be used to identify sebaceous lesions and carcinomas. Journal of Lipid Research. 1997. 38 (11): 2249–63, PMID: 9392423; Trends Endocrinol Metab. 2016 Dec;27(12):893-903, PMID: 27659144; Intl J Clin Exp Med. 2014. 7 (4): 1190–6, PMID: 24955208; Int J Oncol. 2018 Jul; 53(1): 137–147, PMID: 29749470
Target
Human PLIN2 / ADFP / Adipophilin
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:3000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 28 and 281 of Human ADFP.
Specificity
Human ADFP. Predicted cross-reactivity based on amino acid sequence homology: mouse (82%), bovine (86%), pig (87%).
Presentation
0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Storage
Keep as concentrated solution. For short term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PLIN2 / ADFP / Adipophilin
Q99541 NM_001122 NP_001113.2

Validation

Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PathPlus™ Validated
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PathPlus™ Validated
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human liver, lipid droplets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PathPlus™ Validated
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Adipophilin antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Publications (2)

Effect of Maternal Obesity on Placental Lipid Metabolism. Calabuig-Navarro V, Haghiac M, Minium J, Glazebrook P, Ranasinghe GC, Hoppel C, Hauguel de-Mouzon S, Catalano P, O'Tierney-Ginn P. Endocrinology. 2017 August;158:2543-2555.

Inhibition of ß-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82. Lafyatis R, Mantero JC, Gordon J, Kishore N, Carns M, Dittrich H, Spiera R, Simms RW, Varga J. The Journal of investigative dermatology. 2017 December;137:2473-2483.

Reviews (0)

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Requested From: United States
Date Requested: 9/18/2019