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PathPlusTM PLAP / Alkaline Phosphatase Antibodies
PLAP (alkaline phosphatase, placental type, ALPP) is an allosteric enzyme expressed in the placenta. PLAP is a membrane-bound protein that functions to catalyze phosphate monoester hydrolysis and transphosphorylation. In immunohistochemistry of cancer, PLAP is marker used to identify seminoma and malignant germ cell tumors (embryonal carcinoma and dysgerminoma), and it is also positive in ovarian, breast, lung, stomach, and pancreatic carcinomas. In normal tissues, PLAP stains placental trophoblasts.
References: J Phys Chem B. 2014 Dec 11;118(49):14302-13, PMID: 25409280; J Lab Med. 2004. 28 (2): 109–115, DOI:10.1515/labmed.2004.018; Clin. Biochem. 20 (6): 387–92, PMID: 3325192.
2 PathPlusTM Antibodies
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Products
Antibodies
(2)
Type
Primary
(2)
Target
PLAP / Alkaline Phosphatase
(2)
Reactivity
Human
(2)
Application
IHC
(1)
IHC-P
(2)
Host
rabbit
(1)
mouse
(1)
Product Group
PathPlus Cancer
(2)
PathPlus Cancer Pathology
(2)
Isotype
IgG
(2)
Clonality
monoclonal mc
(1)
recombinant monoclonal rmc
(1)
Clone
ALPP/2899R
(1)
Format
Unconjugated
(2)
Publications
No
(2)
Cancer Pathology
Cancer
PLAP / Alkaline Phosphatase Rabbit anti-Human Recombinant Monoclonal (ALPP/2899R) Antibody
Human
IHC-P
Unconjugated
100 µg/$525
Cancer Pathology
Cancer
PLAP / Alkaline Phosphatase Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
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