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PathPlusTM MUC16 / CA125 Antibodies
CA-125 (MUC16) is a mucin glycoprotein expressed by epithelial cells of endometrium, endocervix, pleura, pericardium, and fallopian tube peritoneum. Antibodies to this target are useful for identifying non-mucinous epithelial ovarian carcinomas, serous and endometrioid adenocarcinomas, Krukenberg tumors, and uterine leiomyomas. Elevated levels of serum CA-125 are correlated with the presence or recurrence of ovarian cancer. In immunohistochemistry, MUC16 is positive in the apical brush border of the fallopian tube epithelium, serous ovarian adenocarcinomas and mesotheliomas. It is negative in melanoma, lung and other adenocarcinomas. References: Clin Onc 12:437, 2015; International Journal of Cancer. 2002. 98 (5): 737–40. doi:10.1002/ijc.10250, PMID: 11920644; Expert Review of Molecular Diagnostics. 2010. 10 (8): 1069–83, PMID: 21080822.

2 PathPlusTM Antibodies
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Antibodies (2)
Primary (2)
MUC16 / CA125 (2)
Human (2)
IHC (2)
IHC-P (2)
WB (2)
ELISA (2)
mouse (2)
Product Group
PathPlus Cancer (2)
PathPlus Cancer Pathology (2)
IgG1 (2)
monoclonal mc (2)
X306 (1)
X325 (1)
Unconjugated (2)
Extracellular Domain (1)
No (2)
MUC16 / CA125 Antibody - Anti-MUC16 / CA125 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer Pathology
Cancer
MUC16 / CA125 Mouse anti-Human Monoclonal (Extracellular Domain) (X325) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
MUC16 / CA125 Antibody - Anti-MUC16 / CA-125 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
MUC16 / CA125 Mouse anti-Human Monoclonal (X306) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
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