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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A1339-50 50 µg (1 mg/ml) $425 
TACR1 / NK1R Antibody - Brain, Caudate neuron
TACR1 / NK1R Antibody - Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR1 / NK1R Antibody - Anti-TACR1 /  NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR1 / NK1R Antibody - Brain, Caudate neuron
TACR1 / NK1R Antibody - Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TACR1 / NK1R Antibody - Anti-TACR1 /  NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal TACR1 / NK1R Antibody (Extracellular Domain, IHC) LS‑A1339

PathPlus™ Polyclonal TACR1 / NK1R Antibody (Extracellular Domain, IHC) LS‑A1339

Antibody:
Rabbit Polyclonal to Human TACR1 / NK1R
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A1339-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human TACR1 / NK1R
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Tachykinin Receptor 1 (TACR1) is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. TACR1 is associated with the management of depression, anxiety, and stress. It is furtehr involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. In disease, TACR1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human TACR1 / NK1R
Synonyms
TACR1 | Neurokinin receptor 1 | NK-1R | Nk1 tachykinin receptor | NK1R | TAC1R | Tachykinin 1 receptor | NKIR | Substance-P receptor | Neurokinin 1 receptor | NK-1 receptor | Tachykinin receptor 1
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Dog (tested or 100% immunogen sequence identity)
Predicted
Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2 - 4 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 16 amino acid peptide from 2nd extracellular domain of human Neurokinin 1 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog (100%); Rabbit (94%); Elephant, Horse, Guinea pig (88%); Mouse, Rat, Hamster, Opossum (81%).
Blocking Peptide
LS-E28243 - Liquid - 50 µg 1 mg/ml - $145.00
Immunizing peptide used to generate LS-A1339. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Extracellular Domain
Specificity
Human Neurokinin 1 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TACR1 / NK1R
P25103 NM_001058 NP_001049.1

Validation

TACR1 / NK1R Antibody - Brain, Caudate neuron
Brain, Caudate neuron
Brain, Caudate neuron

TACR1 / NK1R Antibody - Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TACR1 / NK1R Antibody - Anti-TACR1 /  NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR1 / NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR1 / NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 2/23/2020