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| Catalog Number | Size | Price |
|---|---|---|
| LS-B7202-0.1 | 0.1 mg | $485 |
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PathPlus™ Monoclonal Mouse anti‑Bovine Vimentin Antibody (clone RV202, IHC, WB) LS‑B7202
PathPlus™ Monoclonal Mouse anti‑Bovine Vimentin Antibody (clone RV202, IHC, WB) LS‑B7202
Note: This antibody replaces LS-C146793
Antibody:
Vimentin Mouse anti-Bovine Monoclonal (RV202) Antibody
Application:
IHC-P, IHC-Fr, ICC, WB, Flo
Reactivity:
Bovine, Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Pig, Chicken
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
Vimentin Mouse anti-Bovine Monoclonal (RV202) Antibody
Application:
IHC-P, IHC-Fr, ICC, WB, Flo
Reactivity:
Bovine, Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Pig, Chicken
Format:
Unconjugated, Unmodified
Specifications
Description
Vimentin (VIM) is an intermediate filament component of the cytoskeleton of mesenchymal cells. It is important for maintaining cell integrity and shape. Vimentin also regulates cell migration via cytoskeletal rearrangements and is involved in regulating autophagy. In immunohistochemistry, it is positive in the cytoplasm of cells of mesenchymal origin, such as lymphocytes, endothelial cells, astrocytes, epidermal Langerhans cells, macrophages, and interstitial stromal cells. In cancer, it is positive in lymphomas and stromal tumors and is helpful for identifying melanomas, schwannomas and tumors of mesenchymal origin.
References: Am J Surg Pathol. 2011;35:1722, PMID: 21997693; F1000Res. 2018 Nov 15;7. pii: F1000 Faculty Rev-1796, PMID: 30505430; PLoS One. 2019 Jan 30;14(1):e0209665, PMID: 30699149; Toxicol Pathol. 2010 Jan;38(1):131-41, PMID: 20028992
Host
Mouse
Reactivity
Bovine, Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Pig, Chicken
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
RV202
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Cytoskeletal vimentin extract of calf lens.
Specificity
Reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors e.g. lymphoma, sarcoma and melanoma.
Applications
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen (1:100 - 1:200)
- ICC
- Western blot (1:100 - 1:1000)
- Flow Cytometry (1:100 - 1:200)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
About Vimentin
Validation
Anti-Vimentin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Vimentin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ Vimentin Antibody (clone RV202) for IHC, ICC, WB/Western, Flow LS-B7202 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
