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Catalog Number Size Price
LS-B10263-50 50 µg (0.5 mg/ml) $460 
VEGFA / VEGF Antibody - Anti-VEGFA / VEGF antibody IHC staining of human small intestine vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

PathPlus™ Polyclonal Rabbit anti‑Human VEGFA / VEGF Antibody (N‑Terminus, IHC, WB) LS‑B10263

PathPlus™ Polyclonal Rabbit anti‑Human VEGFA / VEGF Antibody (N‑Terminus, IHC, WB) LS‑B10263

Note: This antibody replaces LS-C171715, LS-C312314
Antibody:
VEGFA / VEGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B10263-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
VEGFA / VEGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
VEGFA (vascular endothelial growth factor A) is aglycosylated mitogen that acts on endothelial cells, where it activates cellular proliferation, angiogenesis and migration. It is vital for organ remodeling, vasculogenesis, the regulation of neuronal vascular supply, and endothelial cell differentiation, and it is the primary activator of blood vessel growth. VEGFA is involved in activating PI3K-Akt, MEK-ERK and other downstream signaling pathways, and as an actor in angiogenesis it promotes an increase in microvessel density when overexpressed in cancer. In immunohistochemistry, VEGFA is a marker for tumorigenesis, specifically angiogenesis and proliferation, and is regularly overexpressed in breast and many other cancers. It has cytoplasmic expression in all normal tissues. References: Oncology 2010 Apr; 4; 15-34, PMID: 20567632; Nucleic Acids Research 2016 Jan; 44.D1; D733-745, PMID: 26553804; Development. 2012 Apr;139(8):1371-80, PMID: 22434866;
Target
Human VEGFA / VEGF
Synonyms
VEGFA | VPF | Vascular permeability factor | VEGF | VEGF-A | MVCD1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to a sequence near the N-Terminus end of VEGF of human origin, identical to the related rat sequences.
Epitope
N-Terminus
Specificity
Human, mouse, rat. No cross reactivity with other proteins.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide
Storage
Short term: store at 4°C. Long term: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About VEGFA / VEGF
P15692 NM_003376 NP_003367.4

Validation

VEGFA / VEGF Antibody - Anti-VEGFA / VEGF antibody IHC staining of human small intestine vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-VEGFA / VEGF antibody IHC staining of human small intestine vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-VEGFA / VEGF antibody IHC staining of human small intestine vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ VEGFA / VEGF Antibody (N-Terminus) for IHC, WB/Western LS-B10263 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 7/21/2024