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Catalog Number Size Price
LS-A1520-50 50 µg (1 mg/ml) $460 
TPRA1 / GPR175 Antibody - Brain, glioblastoma
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Brain, hypothalamus
TPRA1 / GPR175 Antibody - Brain, Hippocampus CA4
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Brain, glioblastoma
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Brain, hypothalamus
TPRA1 / GPR175 Antibody - Brain, Hippocampus CA4
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human TPRA1 / GPR175 Antibody (N‑Terminus, IHC) LS‑A1520

PathPlus™ Polyclonal Rabbit anti‑Human TPRA1 / GPR175 Antibody (N‑Terminus, IHC) LS‑A1520

Note: This antibody replaces LS-C67008
Antibody:
TPRA1 / GPR175 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A1520-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
TPRA1 / GPR175 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Gpr175 (also known as TPRA1 or TPRA40: transmembrane protein, adipocyte associated 1 or of 40 kDa) is a GPCR that localizes to primary cilia upon Hh stimulation and positively regulates Hh signaling. Gpr175 or Gai1 depletion leads to increases in cellular cAMP levels and in Gli3 processing into its repressor form. Gpr175 coupled to Gai1 normally functions to inhibit the production of cAMP by adenylyl cyclase upon Hh stimulation, thus maximizing signaling by turning off PKA activity and hence Gli3 repressor formation. References: October 8, 2015 doi: 10.1074/jbc.M115.665810jbc.M115.665810.
Target
Human TPRA1 / GPR175
Synonyms
TPRA1 | G protein-coupled receptor 175 | Transmembrane protein 227 | TMEM227 | TPRA40 | GPR175
Host
Rabbit
Reactivity
Human, Monkey, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bovine, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from N-Terminus extracellular domain of human TPRA1 / GPR175. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rabbit (100%); Dog, Bovine, Elephant, Panda, Horse (94%); Mouse, Rat, Bat, Pig (88%).
Epitope
N-Terminus
Specificity
Human TPRA1 / GPR175. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (9 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TPRA1 / GPR175
Q86W33 NM_016372 NP_057456.2

Validation

TPRA1 / GPR175 Antibody - Brain, glioblastoma
Brain, glioblastoma
Brain, glioblastoma

TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TPRA1 / GPR175 Antibody - Brain, hypothalamus
Brain, hypothalamus
Brain, hypothalamus

TPRA1 / GPR175 Antibody - Brain, Hippocampus CA4
Brain, Hippocampus CA4
Brain, Hippocampus CA4

TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TPRA1 / GPR175 Antibody - Anti-TPRA1 / GPR175 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TPRA1 / GPR175 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ TPRA1 / GPR175 Antibody (N-Terminus) for IHC LS-A1520 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/28/2021