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Catalog Number Size Price
LS-B5528-50 50 µg (0.5 mg/ml) $440 
S100A6 / Calcyclin Antibody - Anti-S100A6 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
S100A6 / Calcyclin Antibody - Immunofluorescence of monoclonal antibody to S100A6 on HeLa cell. [antibody concentration 10 ug/ml]
S100A6 / Calcyclin Antibody - S100A6 monoclonal antibody clone 6B5 Western blot of S100A6 expression in HeLa.
S100A6 / Calcyclin Antibody - Detection limit for recombinant GST tagged S100A6 is approximately 0.03 ng/ml as a capture antibody.
S100A6 / Calcyclin Antibody - Anti-S100A6 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
S100A6 / Calcyclin Antibody - Immunofluorescence of monoclonal antibody to S100A6 on HeLa cell. [antibody concentration 10 ug/ml]
S100A6 / Calcyclin Antibody - S100A6 monoclonal antibody clone 6B5 Western blot of S100A6 expression in HeLa.
S100A6 / Calcyclin Antibody - Detection limit for recombinant GST tagged S100A6 is approximately 0.03 ng/ml as a capture antibody.
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PathPlus™ Monoclonal Mouse anti‑Human S100A6 / Calcyclin Antibody (clone 6B5, IHC, IF, WB) LS‑B5528

PathPlus™ Monoclonal Mouse anti‑Human S100A6 / Calcyclin Antibody (clone 6B5, IHC, IF, WB) LS‑B5528

Note: This antibody replaces LS-C133420
Antibody:
S100A6 / Calcyclin Mouse anti-Human Monoclonal (6B5) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B5528-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
S100A6 / Calcyclin Mouse anti-Human Monoclonal (6B5) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
S100A6 (Calcyclin) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are found in the cytoplasm and/or nucleus of a wide range of cells, where they modulate cell cycle progression and differentiation. S100A6 may stimulate Ca2+-dependent insulin release, prolactin secretion, and exocytosis, and it may also alter stress responses. In the brain, it is primarily expressed in neurons in the amygdala and entorhinal cortex, as well as in some astrocytes. S100A6 is overexpressed in neurodegenerative diseases including Alzheimer’s and amyotrophic lateral sclerosis (ALS, upregulation in astrocytes). Furthermore, chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. In immunohistochemistry, S100A6 has cytoplasmic and nuclear positivity in most tissues throughout the body. References: PLoS One. 2017; 12(1): e0169760, PMID: 28068373; J Comp Neurol. 1999 Feb 8; 404(2):235-57, PMID: 9934997; Cardiovasc Psychiatry Neurol. 2010; 2010: 720958, PMID: 20862335; Journal of Neuropathology & Experimental Neurology. 61( 8). 2002. 736–744, DOI:10.1093/jnen/61.8.736; Front. Neurosci., 2019, DOI: 10.3389/fnins.2019.00463;
Target
Human S100A6 / Calcyclin
Synonyms
S100A6 | 2A9 | 5B10 | CABP | CACY | PRA | MLN 4 | Protein S100-A6 | Calcyclin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
6B5
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
S100A6 (AAH01431, 1 aa ~ 91 aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human S100A6
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (10 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell lysates, cell line lysates and the recombinant protein used as the immunogen.
Presentation
PBS, pH 7.4
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About S100A6 / Calcyclin
P06703 NM_014624 NP_055439.1

Validation

S100A6 / Calcyclin Antibody - Anti-S100A6 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-S100A6 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-S100A6 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ S100A6 / Calcyclin Antibody (clone 6B5) for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B5528 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 6/24/2024