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S100A6 / Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Gene Name: | S100 calcium binding protein A6 |
Synonyms: | S100A6, 2A9, 5B10, CABP, CACY, PRA, MLN 4, Protein S100-A6, Calcyclin |
Target Sequences: | NM_014624 NP_055439.1 P06703 |
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