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Catalog Number Size Price
LS-B13282-50 50 µl (1 mg/ml) $440 
MTOR Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
MTOR Antibody - Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
MTOR Antibody - Human recombinant protein fragment corresponding to amino acids 1766-2144 of human MTOR(NP_004949) produced in E.coli.
MTOR Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
MTOR Antibody - Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
MTOR Antibody - Human recombinant protein fragment corresponding to amino acids 1766-2144 of human MTOR(NP_004949) produced in E.coli.
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PathPlus™ Monoclonal Mouse anti‑Human MTOR Antibody (clone 10B4, aa1766‑2144, IHC, WB) LS‑B13282

PathPlus™ Monoclonal Mouse anti‑Human MTOR Antibody (clone 10B4, aa1766‑2144, IHC, WB) LS‑B13282

Note: This antibody replaces LS-C339853
Antibody:
MTOR Mouse anti-Human Monoclonal (aa1766-2144) (10B4) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B13282-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
MTOR Mouse anti-Human Monoclonal (aa1766-2144) (10B4) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
MTOR (mechanistic target of rapamycin, FRAP1) is a serine/threonine protein kinase that acts as a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Overexpression of MTOR is related to tumorigenesis in breast, lung, bladder, brain, renal, thyroid, and prostate cancer as well as melanoma and leiomyosarcoma, and it is a target of therapeutic inhibitors. In immunohistochemistry of normal tissue, MTOR has membranous and cytoplasmic positivity in epithelial tissues throughout the body including intestinal crypts, the isthmic region of the stomach, pancreatic ductal cells, liver bile ducts, the kidney distal nephron and the bladder. References: Dis Markers. 2017; 2017: 1397063, PMID: 28831205; Mod Pathol 2011;24:1553, PMID: 21822208; Mod Pathol 2012;25:197, PMID:22080063
Target
Human MTOR
Synonyms
MTOR | FRAP1 | FRAP2 | FRAP | Mammalian target of rapamycin | RAFT1 | Rapamycin and FKBP12 target 1 | RAPT1 | Rapamycin target protein 1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Clone
10B4
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Human recombinant protein fragment corresponding to amino acids 1766-2144 of human MTOR(NP_004949) produced in E. coli.
Epitope
aa1766-2144
Specificity
Human MTOR
Applications
  • IHC
  • IHC - Paraffin (1:150) & (10 µg/ml)
  • Western blot (1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MTOR
P42345 NM_004958 NP_004949.1

Validation

MTOR Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

MTOR Antibody - Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ MTOR Antibody (aa1766-2144, clone 10B4) for IHC, WB/Western LS-B13282 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/30/2021